84222-49-1

Basic information

• Product Name: 7-[(1,3-dibenzyloxy-2-propoxy)methyl]guanine
• Synonyms: 7-[(1,3-dibenzyloxy-2-propoxy)methyl]guanine
• CAS NO: 84222-49-1
• Molecular Weight: 435.483
• Mol File: 84222-49-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7-[(1,3-dibenzyloxy-2-propoxy)methyl]guanine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(1,3-dibenzyloxy-2-propoxy)methyl]guanine(84222-49-1)
• EPA Substance Registry System: 7-[(1,3-dibenzyloxy-2-propoxy)methyl]guanine(84222-49-1)

Safety Data

• Hazardous Substances Data: 84222-49-1(Hazardous Substances Data)

Upstream product

• 84222-48-0 N²-acetyl-7-<<1,3-bis(benzyloxy)-2-propoxy>methyl>guanine 
• 74564-16-2 1,3-dibenzyloxy-2-(chloromethoxy)propane 
• 19962-37-9 N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide 
• 18602-85-2 2,6,9-tris(trimethylsilyl)guanine 
• 6972-79-8 dibenzyl glycerol 
• 73-40-5 2-amino-1,9-dihydro-6H-purin-6-one 

Downstream Products

• 84222-50-4 7-(1,3-dihydroxy-2-propoxymethyl)guanine 

Relevant articles and documents

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18F]FHPG)

An improved total synthesis of [18F]FHPG starting from 1,3-dibenzyloxy-2-propanol and guanine has been developed. [18F]FHPG was prepared by nucleophilic substitution of the appropriate precursor with [18F]KF/ Kryptofix 2.2.2 followed by a quick deprotection reaction and purification with a simplified Silica Sep-Pak solid-phase extraction (SPE) method in 10-15% radiochemical yield, and 70 min synthesis time from end of bombardment (EOB).

Biologically active acyclonucleoside analogues. II. The synthesis of 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62)

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