84836-32-8

Usage

InChI:InChI=1/C13H18O2/c1-4-10(5-2)13(14)11-6-8-12(15-3)9-7-11/h6-10H,4-5H2,1-3H3

Upstream product

• 88-09-5 2-Ethylbutanoic acid 
• 100-66-3 methoxybenzene 
• 510-20-3 diethyl malonic acid 
• 97-96-1 2-Ethylbutyraldehyde 
• 5720-07-0 4-methoxyphenylboronic acid 
• 100-07-2 4-methoxy-benzoyl chloride 
• 109-66-0 pentane 
• 2736-40-5 chlorure d'acide ethyl-2 butyrique 

Downstream Products

• 84836-31-7 4-[2-Ethyl-1-(4-fluoro-phenyl)-but-1-enyl]-phenol 
• 1352617-24-3 (E)-2-ethyl-1-(4-methoxyphenyl)-2-buten-1-one 
• 1352617-35-6 2-ethyl-1-(4-methoxyphenyl)but-1-enyl t-butyldimethylsilyl ether 
• 100256-47-1 2-ethyl-1-(4-hydroxy-phenyl)-butan-1-one 

Relevant academic research and scientific papers

Rapid and Direct Photocatalytic C(sp3)?H Acylation and Arylation in Flow

Herein, we report a photocatalytic procedure that enables the acylation/arylation of unfunctionalized alkyl derivatives in flow. The method exploits the ability of the decatungstate anion to act as a hydrogen atom abstractor and produce nucleophilic carbon-centered radicals that are intercepted by a nickel catalyst to ultimately forge C(sp3)?C(sp2) bonds. Owing to the intensified conditions in flow, the reaction time can be reduced from 12–48 hours to only 5–15 minutes. Finally, kinetic measurements highlight how the intensified conditions do not change the reaction mechanism but reliably speed up the overall process.

Synthesis of arylketones by ruthenium-catalyzed cross-coupling of aldehydes with arylboronic acids

The first ruthenium-catalyzed cross-coupling of aldehydes with arylboronic acids is reported. Various aliphatic and aromatic aldehydes are transformed to the corresponding arylketones. A total of 31 examples with moderate to excellent yields are presented, together with the results of an initial mechanistic investigation.

Process for the preparation of aryl ketones generating reduced amounts of toxic byproducts

An efficient, cost-effective method useful for the production of aryl ketones that minimizes the generation of toxic byproducts is disclosed. The method utilizes a metal triflate salt to catalyze the reaction between the carboxylic acid substrate and the aromatic substrate. The water generated by the reaction is collected and removed during the process.