85574-14-7Relevant academic research and scientific papers
One-Pot Synthesis of α-Amino Nitrile Units through Alkylative Strecker Cyanation from Formamides
Yu, Bao,Bodinier, Florent,Saague-Tenefo, Maximiliene,Gerardo, Patrice,Ardisson, Janick,Lannou, Marie-Isabelle,Sorin, Geoffroy
, p. 3634 - 3640 (2021/07/22)
In this work, we describe the one-pot synthesis of α-amino nitrile units by the concomitant addition of alkyl (or aryl) Grignard reagents and TMS cyanide through alkylative Strecker cyanation from readily available formamides. The reaction is broad in sco
Sulfamic acid: an efficient, cost-effective and recyclable solid acid catalyst for the three-component synthesis of α-amino nitriles
Heydari, Akbar,Khaksar, Samad,Pourayoubi, Mehrdad,Mahjoub, Ali Reza
, p. 4059 - 4060 (2008/02/03)
α-Amino nitriles are synthesized by the three-component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using sulfamic acid as a heterogeneous solid acid catalyst, under solvent-free conditions in excellent yields. The catalyst was recov
CHEMICAL COMPOUNDS
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Page 123, (2010/02/06)
Compounds of formula (I):wherein variable groups are as defined within; for use in the inhibition of 11betaHSD1 are described
Bis(dialkylamino)cyanoboranes: Highly efficient reagents for the Strecker-type aminative cyanation of aldehydes and ketones
Suginome, Michinori,Yamamoto, Akihiko,Ito, Yoshihiko
, p. 1392 - 1393 (2007/10/03)
a-Dialkylamino nitriles are formed in excellent yields in the reactions of bis(dialkylamino)cyanoboranes with a wide array of carbonyl compounds.
Lithium perchlorate/diethylether catalyzed aminocyanation of aldehydes
Heydari, Akbar,Fatemi, Parinaz,Alizadeh, Abdol-Ali
, p. 3049 - 3050 (2007/10/03)
A simple and efficient one-pot method was developed to give α- aminonitriles from aldehydes + amines + TMSCN in LPDE. Optically active α- aminonitriles were snythesized by using (S)-(-)- or (R) (+) α- methylbenzylamine, (S)-(-) α-methylbenzylamine affords
