857040-74-5Relevant articles and documents
Enzyme-Loaded Hemin/G-Quadruplex-Modified ZIF-90 Metal–Organic Framework Nanoparticles: Bioreactor Nanozymes for the Cascaded Oxidation of N-hydroxy-l-arginine and Sensing Applications
Chen, Chaochao,O'Hagan, Michael P.,Ouyang, Yu,Vázquez-González, Margarita,Wang, Zhanhui,Willner, Itamar
, (2022/01/19)
Biocatalytic cascades are challenging to operate in homogeneous solution, where diffusional mass transport hinders efficient communication between the reactive components. There is great interest in developing devices to perform such transformations in co
Visible-Light-Mediated Dearomatisation of Indoles and Pyrroles to Pharmaceuticals and Pesticides
Schilling, Waldemar,Zhang, Yu,Riemer, Daniel,Das, Shoubhik
supporting information, p. 390 - 395 (2019/12/15)
Dearomatisation of indole derivatives to the corresponding isatin derivatives has been achieved with the aid of visible light and oxygen. It should be noted that isatin derivatives are highly important for the synthesis of pharmaceuticals and bioactive compounds. Notably, this chemistry works excellently with N-protected and protection-free indoles. Additionally, this methodology can also be applied to dearomatise pyrrole derivatives to generate cyclic imides in a single step. Later this methodology was applied for the synthesis of four pharmaceuticals and a pesticide called dianthalexin B. Detailed mechanistic studies revealed the actual role of oxygen and photocatalyst.
Palladium Supported on Carbon Nanoglobules as a Promising Catalyst for Selective Hydrogenation of Nitroarenes
Mironenko,Belskaya,Stepanova,Gulyaeva,Trenikhin,Likholobov
, p. 888 - 900 (2019/11/11)
The catalysts 1?wt% palladium supported on carbon nanoglobules (CNGs) were shown to be highly active in the liquid-phase hydrogenation of various nitroarenes and provided nearly 100% selectivity to aromatic amines at complete conversion under mild conditions (323?K, 0.5?MPa, 1?h). The catalytic activity (in terms of turnover frequency and substrate conversion) and selectivity depend on the kind of CNGs support, catalyst preparation method and the reaction conditions (solvent nature). The Pd/CNGs catalyst can be repeatedly used while maintaining the same catalytic performance. The excellent performances of Pd/CNGs catalysts can be due to the globular morphology of the supports as well as the absence of micropores and pronounced surface defects. Graphic Abstract: [Figure not available: see fulltext.]