866038-49-5

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetate is used as a potential pharmaceutical compound for its possible biological activities. Its role in plant defense mechanisms suggests that it may have applications in medicine, although further research is needed to explore its full potential.
Used in Agriculture:
Methyl 2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetate is used in agriculture for its potential role in plant defense against pests and pathogens. Its presence in benzoxazinoids, which are known for their protective properties in plants, indicates that it may be a valuable tool for enhancing crop resistance and reducing the need for chemical pesticides.

Upstream product

• 1455471-90-5 ethyl 2-(4-(2-methoxy-2-oxoethyl)-2-nitrophenoxy)acetate 
• 10463-20-4 4-hydroxy-3-nitrophenylacetic acid 
• 156-38-7 4-hydroxyphenylacetate 
• 104-01-8 4-Methoxyphenylacetic acid 
• 61873-93-6 methyl (4-hydroxy-3-nitrophenyl)acetate 
• 34837-88-2 methyl 2-(4-methoxy-3-nitrophenyl)acetate 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 78587-72-1 methyl (3-amino-4-hydroxyphenyl)acetate 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 134997-91-4 2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)acetic acid 

Relevant academic research and scientific papers

N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXA ZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES

The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl] (phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases or cholestatic diseases, such as e.g. arthitis and asthma.

SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS

The present invention relates to a series of substituted compounds having the general formula (I), including their ste reoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3. R4, R5, and R6 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (κ) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS.

Substituted Spiroamide Compounds

Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).