877-94-1

Upstream product

• 60773-92-4 β-benzalpropionic acid chloride 
• 18815-73-1 methylzinc iodide 
• 141-78-6 ethyl acetate 
• 71-43-2 benzene 
• 1095-80-3 (α-methoxyethyl)triphenylphosphonium chloride 
• 104-55-2 3-phenyl-propenal 
• 69803-55-0 1-(Diphenylphosphinyl)butan-3-one ethylene ketal 
• 100-52-7 benzaldehyde 
• 28987-86-2 ((1E,3Z)-4-Nitro-penta-1,3-dienyl)-benzene 
• 536-74-3 phenylacetylene 
• 67-64-1 acetone 
• 201230-82-2 carbon monoxide 
• 2687-12-9 cinnamyl chloride 
• 74-88-4 methyl iodide 

Downstream Products

• 40398-05-8 5-benzylcyclohexane-1,3-dione 
• 100-52-7 benzaldehyde 
• 134418-83-0 (E)-3-diazo-5-phenylpent-4-en-2-one 
• 17357-78-7 1-(5-phenyl-1H-pyrazol-3-yl)ethan-1-one 
• 7063-98-1 3-acetyl-5-phenyl-isoxazole 
• 40468-35-7 O,O-Aethyl-isopropyl-1-(phenyl)-3-hydroxy-2-butenylphosphonat 

Relevant academic research and scientific papers

Synthesis of 3-Acyl-Isoxazoles via Radical 5-endo trig Cyclization of β,γ-Unsaturated Ketones with NaNO2

Here we report a facile cyclization reaction of β,γ-unsaturated ketones with NaNO2 under mild conditions to construct 3-acyl-isoxazoles. This transformation is realized via nitrosation of the activated methylene, radical 5-endo trig cyclization

Intramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles

Vinyldiazo compounds undergo a thermal electrocyclization to form pyrazoles in yields of up to 95percent. The reactions are operationally simple, use readily available starting materials, require no intervention of a catalyst, and enable the synthesis of mono-, di- A nd tri-substituted pyrazoles. With the ability to produce highly substituted pyrazoles and the flexibility in installing various types of substituents, this method constitutes a new entry to this valuable heterocyclic scaffold and may be of interest to all branches of the chemical industry.

In/InCl3-mediated cross-coupling reactions of methyl vinyl ketone with benzaldehyde in aqueous media

(matrix presented) Various β,γ-unsaturated ketones were successfully prepared by cross-coupling reactions of methyl vinyl ketone (MVK) with benzaldehydes mediated by In/InCl3 in aqueous media.

Phase Transfer Generation of Acyltetracarbonyliron Anions: their Role in the Phase Transfer Carbonylation of Reactive Halides to give Carboxylic Acids and Symmetrical and Unsymmetrical Ketones

Acyltetracarbonyliron anions RCOFe(CO)4(1-) (3) are readily synthesised under mild phase transfer (PT) conditions from pentacarbonyliron and reactive organic halides; the in situ generated anions (3) (R = ArCH2) are the true catalysts in the PT carbonylation of benzyl halides to give ketones or carboxylic acids.

REDUCTIVE CONVERSION OF NITRO ALKENES TO KETONES AND/OR OXIMES IN AN AQUEOUS HClO4-CH2Cl2-DIOXANE-(Pb) SYSTEM

Electrochemical and chemical reduction of nitro alkenes in an aqueous HClO4-CH2Cl2-dioxane-(Pb) system afforded ketones and oximes in good yields, each of which can be obtained selectively by treating with either aqueous formaldehyde or hydroxylamine as a proper workup process, respectively.

ADDITION DE L'ACETONE A DES ALCYNES VRAIS FONCTIONNELS OU NON

Acetonyl radicals created by action of di-t-butylperoxide on acetone (molar ratios acetone/acetylenic compound/DTBP = 20/1/0.2 ; 150 deg C ; 3h) add to acetylenic compounds and lead to the formation of 1/1 adducts in low to moderate yields. 2/1 adducts ar