877997-98-3

Basic information

• Product Name: PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE
• Synonyms: Benzoic acid,2-hydroxy-4,5-dimethoxy-,phenyl ester (for Acotiamide);Benzoic acid,2-hydroxy-4,5-dimethoxy-,phenyl ester;Ethyl 2-(2-hydroxy-4,5-diMethoxybenzaMido)thiazole-4-carboxylate;PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE;2-Hydroxy-4,5-dimethoxybenzoic acid phenyl ester;Phenyl 2-hydroxy-4,5-dimethoxybenzoate Benzoic acid,2-hydroxy-4,5-dimethoxy-,phenyl ester (for Acotiamide)
• CAS NO: 877997-98-3
• Molecular Formula: C₁₅H₁₄O₅
• Molecular Weight: 274.27
• EINECS: 1806241-263-5
• Mol File: 877997-98-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 431.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.250±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.83±0.23(Predicted)
• CAS DataBase Reference: PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE(877997-98-3)
• EPA Substance Registry System: PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE(877997-98-3)

Safety Data

• Hazardous Substances Data: 877997-98-3(Hazardous Substances Data)

Usage

General Description

PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE is an organic compound that belongs to the class of benzoate esters. It is a white crystalline powder that is used in various industries as a flavoring agent, fragrance ingredient, and UV filter in sunscreen products. This chemical is also known for its potential antioxidant and anti-inflammatory properties. It is commonly used in the formulation of cosmetic and personal care products, as well as in the food and beverage industry. PHENYL 2-HYDROXY-4,5-DIMETHOXYBENZOATE is considered to be safe for use in these applications when used in accordance with regulations and guidelines set by regulatory authorities.

Upstream product

• 101-02-0 triphenyl phosphite 
• 5722-93-0 2-hydroxy-4,5-dimethoxybenzoic acid 
• 61203-48-3 2-iodo-4,5-dimethoxybenzoic acid 
• 6286-46-0 2-bromo-4,5-dimethoxybenzoic acid 
• 93-07-2 Veratric acid 
• 108-95-2 phenol 

Downstream Products

• 877997-99-4 2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxylic acid methyl ester 
• 185104-11-4 2-[N-(4,5-dimethoxy-2-hydroxybenzoyl)amino]-4-[(2-diisopropyl-aminoethyl)aminocarbonyl]-1,3-thiazole hydrochloride 
• 185106-16-5 Acotiamide 
• 877998-00-0 CH₄O*C₁₄H₁₄N₂O₆S 

Relevant articles and documents

arab League tests for the amine and a method for the preparation of its hydrochloride (by machine translation)

The invention discloses a arab League tests for the amine method for preparing and its hydrochloride, 2 - [(2-hydroxy -4,5-dimethoxy-benzoyl) amino] - 1,3-thiazole-4-carboxylic acid methyl ester, and N, N-diisopropyl ethylenediamin in the molten state after reaction under N-[ 2 - (diisopropyl amino) ethyl] - 2 - [(2-hydroxy -4,5-dimethoxy-benzoyl) amino] - 1,3-thiazole-4-carboxamide, hydrochloric acid for hydrochloric acid prepared by adding dropwisely added methanol trihydrate arab League takes a test for somebody else the amine, the technical proposal of the present invention reduces the use of toluene, economic and convenient, the reaction is complete, process safety; reduced at the same time the residual toluene in the final product, and impurity 2 - [(2-hydroxy -4,5-dimethoxy-benzoyl) amino] - 4-carboxyl -1, the content of 3-thiazole, the product quality is promoted; and is easy to be refined and purification of the crude product, the reaction yield is high. (by machine translation)

METHOD FOR PRODUCING AMINOTHIAZOLE DERIVATIVE AND PRODUCTION INTERMEDIATE

Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.