889675-05-2 Usage
Uses
Used in Organic Chemistry:
1-(4-(Benzyloxy)-1-(phenylsulfonyl)-1H-indol-2-yl)ethanone is used as a versatile building block for the synthesis of new chemical compounds due to its multi-functional structure and the presence of various functional groups.
Used in Pharmaceutical Industry:
1-(4-(Benzyloxy)-1-(phenylsulfonyl)-1H-indol-2-yl)ethanone is used as a precursor in the development of pharmaceutical products, leveraging its potential for biological activity and its ability to be modified for specific therapeutic applications.
Used in Material Science:
1-(4-(Benzyloxy)-1-(phenylsulfonyl)-1H-indol-2-yl)ethanone is used in the design and synthesis of novel materials with unique properties, taking advantage of its complex structure and functional groups to create materials with specific characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 889675-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,6,7 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 889675-05:
(8*8)+(7*8)+(6*9)+(5*6)+(4*7)+(3*5)+(2*0)+(1*5)=252
252 % 10 = 2
So 889675-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C23H19NO4S/c1-17(25)22-15-20-21(24(22)29(26,27)19-11-6-3-7-12-19)13-8-14-23(20)28-16-18-9-4-2-5-10-18/h2-15H,16H2,1H3
889675-05-2Relevant academic research and scientific papers
The first potent inhibitor of mammalian group X secreted phospholipase A2: Elucidation of sites for enhanced binding
Smart, Brian P.,Oslund, Rob C.,Walsh, Laura A.,Gelb, Michael H.
, p. 2858 - 2860 (2007/10/03)
Using the X-ray structure of human group X secreted phospholipase A 2 (hGX), we carried out structure-based design of indole-based inhibitors and prepared the compounds using a new synthetic route. The most potent compound inhibited hGX and the mouse orthologue with an IC50 of 75 nM. This compound is the most potent hGX inhibitor reported to date and was also found to inhibit a subset of the other mouse and human SPLA 2S.
