889675-08-5 Usage
Uses
Used in Organic Synthesis:
Tert-butyl 2-[1-benzyl-3-(carbaMoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxyacetate is used as a synthetic intermediate for the creation of various organic compounds. Its unique structure allows for versatile reactions and modifications, facilitating the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, tert-butyl 2-[1-benzyl-3-(carbaMoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxyacetate is used as a research compound for the development of new drugs. Its indole-based structure and functional groups may contribute to the discovery of novel therapeutic agents with potential applications in treating various diseases.
Used in Chemical Research:
Tert-butyl 2-[1-benzyl-3-(carbaMoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxyacetate is employed as a research tool in the field of chemistry to study the reactivity and properties of complex organic molecules. Its detailed structure provides insights into the behavior of similar compounds and aids in understanding the underlying chemical principles.
Check Digit Verification of cas no
The CAS Registry Mumber 889675-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,6,7 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 889675-08:
(8*8)+(7*8)+(6*9)+(5*6)+(4*7)+(3*5)+(2*0)+(1*8)=255
255 % 10 = 5
So 889675-08-5 is a valid CAS Registry Number.
InChI:InChI=1/C25H28N2O5/c1-5-17-22(23(29)24(26)30)21-18(27(17)14-16-10-7-6-8-11-16)12-9-13-19(21)31-15-20(28)32-25(2,3)4/h6-13H,5,14-15H2,1-4H3,(H2,26,30)
889675-08-5Relevant academic research and scientific papers
Regioselective synthesis of 4- and 7-alkoxyindoles from 2,3-dihalophenols: Application to the preparation of indole inhibitors of phospholipase A 2
Sanz, Roberto,Castroviejo, M. Pilar,Guilarte, Veronica,Perez, Antonio,Fananas, Francisco J.
, p. 5113 - 5118 (2008/02/05)
(Chemical Equation Presented) An efficient and regioselective synthesis of 4- and 7-alkoxyindoles has been developed from commercially available starting materials such as 3-halophenols and 3-chloroanisole. Directed ortho-metalation followed by two pallad
The first potent inhibitor of mammalian group X secreted phospholipase A2: Elucidation of sites for enhanced binding
Smart, Brian P.,Oslund, Rob C.,Walsh, Laura A.,Gelb, Michael H.
, p. 2858 - 2860 (2007/10/03)
Using the X-ray structure of human group X secreted phospholipase A 2 (hGX), we carried out structure-based design of indole-based inhibitors and prepared the compounds using a new synthetic route. The most potent compound inhibited hGX and the mouse orthologue with an IC50 of 75 nM. This compound is the most potent hGX inhibitor reported to date and was also found to inhibit a subset of the other mouse and human SPLA 2S.
