89809-89-2

Basic information

• Product Name: 5-ACETYL-2-AMINO-6-METHYL-4-PHENYL-4H-PYRAN-3-CARBONITRILE
• Synonyms: 5-ACETYL-2-AMINO-6-METHYL-4-PHENYL-4H-PYRAN-3-CARBONITRILE;Acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbon
• CAS NO: 89809-89-2
• Molecular Formula: C₁₅H₁₄N₂O₂
• Molecular Weight: 254.28
• Mol File: 89809-89-2.mol
• Article Data: 25

Chemical Properties

• Melting Point: 210 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
• Boiling Point: 503.3°C at 760 mmHg
• Flash Point: 258.2°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 2.95E-10mmHg at 25°C
• Refractive Index: 1.6
• PKA: 2.82±0.70(Predicted)
• CAS DataBase Reference: 5-ACETYL-2-AMINO-6-METHYL-4-PHENYL-4H-PYRAN-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ACETYL-2-AMINO-6-METHYL-4-PHENYL-4H-PYRAN-3-CARBONITRILE(89809-89-2)
• EPA Substance Registry System: 5-ACETYL-2-AMINO-6-METHYL-4-PHENYL-4H-PYRAN-3-CARBONITRILE(89809-89-2)

Safety Data

• Hazardous Substances Data: 89809-89-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14N2O2/c1-9(18)13-10(2)19-15(17)12(8-16)14(13)11-6-4-3-5-7-11/h3-7,14H,17H2,1-2H3

Upstream product

• 4335-90-4 3-benzylidene acetylacetone 
• 109-77-3 malononitrile 
• 100-52-7 benzaldehyde 
• 123-54-6 acetylacetone 
• 105-45-3 acetoacetic acid methyl ester 
• 2700-22-3 Benzylidenemalononitrile 

Downstream Products

• 116418-11-2 2-amino-3-cyano-4-phenyl-5-(2-amino-3-ethoxycarbonyl-4-phenyl-4H-pyran-6-yl)-6-methyl-4H-pyran 
• 1610831-64-5 4-acetyl-2-cyano-5-methyl-3-phenyl-2,3-dihydrofuran-2-carboxamide 
• 107752-97-6 2-amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 
• 81829-58-5 2-amino-5-benzoyl-4,6-diphenyl-4H-pyran-3-carbonitrile 
• 116418-07-6 2-amino-3-cyano-4-phenyl-5-(2-amino-3-cyano-4-phenyl-4H-pyran-6-yl)-6-methyl-4H-pyran 
• 81000-11-5 6-amino-1,4-dihydro-3-methyl-4-phenylpyrano[2,3-c]pyrazole-5-carbonitrile 
• 136773-44-9 3-Acetyl-5-amino-4,7-diphenyl-2-methyl-4H-pyrano<2,3-b>pyridine-6-carbonitrile 
• 2700-22-3 Benzylidenemalononitrile 
• 60989-51-7 2-imino-4,6-dimethyl-2H-pyran-3-carbonitrile 
• 116418-10-1 6-acetyl-4-N-benzoylamino-1,2-dihydro-7-methyl-5-phenyl-2-thioxo-5H-pyrano<2,3-d>pyrimidine 
• 116418-14-5 2,4-dimethyl-5-cyano-3-(1-phenyl-2-dicyanoethyl)-2H-pyran-6-one 
• 117226-91-2 5-acetyl-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyridine-3-carbonitrile 
• 117227-02-8 3-acetyl-6-amino-5-cyano-2-methyl-4-phenylpyridine 
• 115041-50-4 5-Amino-3-acetyl-4,7-diphenyl-2-methyl-6,7-dihydro-4H-pyrano<2,3-b>pyridine-6,6-dicarbonitrile 

Relevant articles and documents

A novel bridgehead azocine. The end of a controversy

A novel bridgehead azocine 4 has been obtained from aminopyran 1 and benzylidinemalononitrile 6. The structure of 4 was confirmed by X-ray diffraction.

Ferric Sulfasalazine Sulfa Drug Complex Supported on Cobalt Ferrite Cellulose; Evaluation of Its Activity in MCRs

Abstract: The green and nano catalyst was simply prepared through the reaction of ferric sulfasalazine with nanomaterial CoFe2O4-cellulose as a magnetic biopolymer surface. This novel heterogeneous organometallic catalyst was charact

Biocatalytic tandem multicomponent reactions for one-pot synthesis of 2-Amino-4H-Pyran library and in vitro biological evaluation

A simple, effective and ecofriendly biocatalytic method has been developed to construct 2-amino-4H-pyrans via tandem multi-component reaction (MCR) of aldehyde, malononitrile and ethyl acetoacetate in one pot. The catalytic activity of lipases in differen

Synthesis method of 2-amino-4H-pyran and derivative of 2-amino-4H-pyran

The invention discloses a synthesis method of 2-amino-4H-pyran and a derivative of the 2-amino-4H-pyran. According to the method, candida rugosa lipase (CRL) is adopted as a catalyst to initiate a tandem MCR reaction, and 2-amino-4H-pyran is synthesized i