107752-97-6

Upstream product

• 2700-22-3 Benzylidenemalononitrile 
• 126-81-8 dimedone 
• 31771-33-2 2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine 
• 3471-13-4 dimedone 
• 109-77-3 malononitrile 
• 100-52-7 benzaldehyde 
• 89809-89-2 5-acetyl-2-amino-3-cyano-6-methyl-4-phenyl-4H-pyran 
• 100-39-0 benzyl bromide 
• 28746-58-9 2-benzylidene-5,5-dimethylcyclohexane-1,3-dione 
• 2235-08-7 Propargyl nitrile 

Downstream Products

• 1043385-59-6 2,8,8-trimethyl-5-phenyl-5,7,8,9-tetrahydro-4H-chromeno[2,3-d]pyrimidine-4,6(3H)-dione 
• 156177-00-3 2-acetylamino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 
• 1610831-41-8 sec-butyl 2-cyano-6,6-dimethyl-4-oxo-3-phenyl-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 
• 1610831-40-7 butyl 2-cyano-6,6-dimethyl-4-oxo-3-phenyl-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 
• 1610831-39-4 isopropyl 2-cyano-6,6-dimethyl-4-oxo-3-phenyl-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 
• 1610831-38-3 propyl 2-cyano-6,6-dimethyl-4-oxo-3-phenyl-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 
• 1610831-37-2 methyl 2-cyano-6,6-dimethyl-4-oxo-3-phenyl-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 

Relevant academic research and scientific papers

A novel anionic di-oxido vanadium(V) Schiff base complex: Synthesis, spectral characterization, X ray crystal structure, catalytic activity for the preparation of tetrahydro-4H-chromene derivatives and antibacterial properties

In this work, a tridentate ONO Schiff base ligand,1-[(((2-hydroxyphenyl)imino)methyl)]naphthalen-2-ol [H2L] and its di-oxido vanadium(V) complex [(VO2(L)](NHET3) have been synthesized and fully characterized using elementa

Surface modified novel magnetically tuned halloysite functionalized sulfonic acid: synthesis, characterization and catalytic activity

This work presents preparation of a surface modified magnetically tuned solid acid where thiol groups were grafted on magnetic halloysite, followed by oxidation of thiol groups to sulfonic acid groups. The physicochemical properties of the catalyst were a

A general and inexpensive protocol for the nanomagnetic 5-sulfosalicylic acid catalyzed the synthesis of tetrahydrobenzo[b]pyrans and quinoxaline derivatives

In this study, a novel acid-functionalized magnetic nanoparticles with high loaded multifunctional acidic groups was fabricated by anchoring water-soluble 5-sulfosalicylic acid onto the surface silica-modified Fe3O4. The magnetically recyclable Fe3O4@SiO2@5-SA (20?mg) showed excellent reactivity for greener synthesis of tetrahydrobenzo[b]pyrans via a three-component reaction of different aromatic aldehydes, malononitrile and dimedone in good to excellent yields (70–95percent) in pure water at short reaction times (40–150?min). The method shows eco-friendly synthesis of quinoxaline derivatives from direct condensation of substituted 1,2-diamine with various 1,2-dicarbonyl in ethanol at room temperature to afford the desired quinoxalines with good to excellent yields (60–97percent) at shorter reaction times (120–240?min). The morphology and magnetic properties of MNPs were studied with scanning electron microscopy, X-ray powder diffraction, Fourier translation infrared spectroscopy, vibrating sample magnetometer and thermogravimetric. The results showed that the Fe3O4@SiO2@5-SA catalyst is completely recoverable by an external magnet and retained catalytic activity after five recycles.

Simplified approach to the uncatalyzed knoevenagel condensation and michael addition reactions in water using microwave irradiation

Use of microwave irradiation in the synthesis of arylidenemalononitrile and benzopyran derivatives in water without catalyst is a clean method with high yield. Copyright Taylor & Francis Group, LLC.

A facile and efficient synthesis of new polysubstituted indeno[1,2-b]pyridines via one-pot, three-component microwave-assisted reaction

A rapid and efficient method is developed to synthesize new polysubstituted indeno[1,2-b]pyridines via three-component microwave-assisted reaction of arylidenemalononitrile, 1,3-indanedione and aromatic amine. This method has the advantages of short synth

Synthesis of nanoparticles silica supported sulfuric acid (NPs SiO 2-H2SO4): A solid phase acidic catalyst for one-pot synthesis of 4H-chromene derivatives

Nanostructured SiO2-H2SO4 has been prepared and shown to efficiently catalyse the one-pot, three-component reaction of an aromatic aldehyde, malononitrile and a cyclic 1,3-diketone at reflux, to afford the corresponding 4H

A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes

A facile one-pot expeditious synthesis of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes has been described under solvent-free conditions using magnesium oxide as a catalyst in very good yields. The reaction catalyst, magnesium oxide

Organocatalyzed domino reactions: diversity oriented synthesis of pyran-annulated scaffolds using in situ-developed benzylidenemalononitriles

Molecular diversity for the synthesis of pyran annulated heterocyclic scaffolds has been achieved from the multicomponent reaction of aldehyde, malonitrile and a third participant such as dimedone, barbituric acid and 3-methyl-1H-pyrazol-5(4H)-one. The re

An Effective One-Pot Access to 2-Amino-4H-benzo[b]pyrans and 1,4-Dihydropyridines via γ-Cyclodextrin-Catalyzed Multi-Component Tandem Reactions in Deep Eutectic Solvent

Abstract: A simple, highly efficient and green route for the synthesis of 2-amino-4H-benzo[b]pyrans and 1,4-dihydropyridines has been developed by using γ-cyclodextrin (γ-CD) as catalyst in deep eutectic solvent (DES) of urea-choline chloride (urea-ChCl),

Amberlite IRA-400 (OH-) as a catalyst in the preparation of 4h-benzo[b]pyrans in aqueous media

A quaternary ammonium hydroxide-type of anion exchange resin (Amberlite IRA-400) was found to be an effective and reusable catalyst for the synthesis of various 4H-benzo[b]pyran derivatives via a one-pot, three-component condensation in aqueous media. Sho