918-79-6

Upstream product

• 124-04-9 Adipic acid 
• 43079-80-7 3-(α-hydroxy-isobutoxy)-2,2,4-trimethyl-valeraldehyde 
• 64-19-7 acetic acid 
• 78-84-2 isobutyraldehyde 
• 74-86-2 acetylene 
• 60-29-7 diethyl ether 
• 151-50-8 potassium cyanide 
• 513-42-8 3-hydroxy-2-methyl-1-propene 

Downstream Products

• 144-19-4 2,2,4-trimethylpentan-1,3-diol 
• 5842-49-9 2,2,4-trimethyl-pent-3-enal 
• 78-84-2 isobutyraldehyde 
• 79-31-2 isobutyric Acid 
• 18300-78-2 diisobutylidene-hydrazine 
• 16889-18-2 5,5-dimethyl-2,6-bis(propan-2-yl)-1,3-dioxan-4-ol 
• 5637-00-3 N,N'-diphenyl-isobutylidenediamine 
• 27122-59-4 2,4,4-trimethyl-heptane-3,5-diol 
• 565-80-0 2,4-dimethylpentan-3-one 

Relevant academic research and scientific papers

Trimerization of aldehydes with one α-hydrogen catalyzed by sodium hydroxide

Trimerization of 2-methylpropanal (isobutyraldehyde) is a simple and effective method to synthesize 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate and 2,2,4-trimethyl-1,3-pentanediol-3-monoisobutyrate which are often used as film forming auxiliaries in paints. The use of solid sodium hydroxide as a catalyst provides an excellent yield of above 85 % after the optimization of the reaction time and the catalyst dosage. Furthermore, trimerization of four other aldehydes with one α-hydrogen catalyzed by solid sodium hydroxide can also take place and the yield of 1,3-diol monoesters reaches 50-70 %. Trimerization of aldehydes with one α-hydrogen can be explained by a three-step reaction mechanism: (i) aldol condensation of aldehyde; (ii) crossed Cannizzaro reaction; and (iii) esterification of carboxylic acid and alcohol.

Redox isomerization of allylic alcohols catalyzed by osmium and ruthenium complexes containing a cyclopentadienyl ligand with a pendant amine or phosphoramidite group: X-ray structure of an η3-1-hydroxyallyl- metal-hydride intermediate

Complexes [MCl2(η6-p-cymene)]2 (M = Os (1a), Ru (1b)) react with Li(C5H4CH2CH 2NHMe) (LiCpN) and KPF6 to give the sandwich derivatives [M(η5-CpN)(η6-p-cymene)] PF6 (M = Os (2a), Ru (2b)). Treatment of 2a and 2b with (2,2--biphenol)PCl leads to [M(η5-CpP) (η6-p-cymene)]PF6 (M = Os (3a), Ru (3b); Cp P = C5H4CH2CH2N(Me)P(2,2- -biphenol)). The photolysis of 2a, 2b, 3a, and 3b in acetonitrile produces the release of the p-cymene group and the coordination of the cyclopentadienyl pendant substituent to the metal center to afford [M(η5-C 5,κ-N-CpN)(CH3CN)2]PF 6 (M = Os (4a), Ru (4b)) and [M(η5-C 5,κ-P-CpP)(CH3CN)2]PF 6 (M = Os (5a), Ru (5b)). Complex 4a, which has been characterized by X-ray diffraction analysis, is a more efficient catalyst precursor than 4b for the redox isomerization of primary allylic alcohols, while the latter is more efficient than the former for the redox isomerization of secondary allylic alcohols. From the catalytic solutions containing 4a and 2-methyl-2-propen-1-ol, the η3-1-hydroxyallyl complex [OsH(η5-C 5,κ-N-CpN){η3-CH2C(CH 3)CHOH}]PF6 (6) has been crystallized and characterized by spectroscopic methods and X-ray diffraction analysis. The structure shows a N-HO hydrogen bond (2.22 a) between the NH-hydrogen atom of the coordinated pendant amine group and the oxygen atom of the hydroxy substituent of the allyl ligand.

COMPOUNDS FOR THE CONTROLLED RELEASE OF ACTIVE ALDEHYDES

The present invention relates to the field of perfumery. More particularly, it concerns an aldoxane derivative of Formula (I) capable of protecting an active aldehyde R1CHO, for example a perfumery or flavor aldehyde, from a chemically aggressive medium into which they have to be added, and then of releasing said active aldehyde at the desired moment. The present invention concerns also the use of said compound in perfumery or in the flavor industry as well as the compositions or articles associated with said aldoxanes.

Synthesis of 1,3,5-trioxanes: A new, simple method using a bentonitic earth as catalyst

A simple method for synthesizing aliphatic as well as aromatic 1,3,5-trioxanes using as catalyst a bentonitic earth is reported. The yields ranged from good to excellent.