91958-55-3

Upstream product

• 603-67-8 diethyl nitromalonate 
• 3506-36-3 3-dimethylaminopropiophenone 
• 626-35-7 nitroacetic acid ethyl ester 
• 768-03-6 Phenyl vinyl ketone 
• 94-38-2 3-diethylamino-1-phenyl-propan-1-one 

Downstream Products

• 952-27-2 5-Ethoxycarbonyl-2-phenyl-Δ¹-pyrroline 
• 212265-33-3 ethyl 2-phenyl-1-pyrroline-5-carboxylate 1-oxide 
• 13355-43-6 5-phenyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 952-26-1 ethyl 5-phenylpyrrolidine-2-carboxylate 
• 212263-60-0 ethyl 2-phenyl-5-(prop-2'-en-1'-yl)-1-pyrroline-5-carboxylate 1-oxide 

Relevant academic research and scientific papers

Synthesis of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate Derivatives and evaluation of their antimalarial activities

Derivatives of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate (14-20), with side chains varying from three to five carbon atoms and bearing various substituents, have been prepared from ethyl 2-phenyl-1-pyrroline-5-carboxylate (12). Their in

Base-free conjugate addition of aliphatic nitro compounds to enones in BmimNTf2: A recyclable synthesis of γ-nitro ketones

A base-free, recyclable approach for the conjugate addition of aliphatic nitro compounds to enones to give γ-nitro ketones is presented. Reactions are carried out in an ionic liquid with a basic anionic moiety, such as BmimNTf2, as the solvent,

Synthesis and reactivity of 1-pyrroline-5-carboxylate ester 1-oxides

Some C5 mono- and diester-substituted 1-pyrroline-1-oxides have been prepared via reductive cyclisation of the corresponding γ-nitro carbonyl compounds. Ethyl 2-phenyl-1-pyrroline-1-oxide-5-carboxylate 5c was regioselectively alkylated at C5. Acylation of this molecule occurs exclusively on the nitrone oxygen and leads to C3 substituted pyrrolines as the result of a hetero-Cope rearrangement. (C) 2000 Elsevier Science Ltd.