13355-43-6

Upstream product

• 125173-15-1 6-Phenyl-6-trimethylsilanyloxy-5,6-dihydro-4H-[1,2]oxazine-3-carboxylic acid ethyl ester 
• 153783-23-4 (S)-5-Ethoxycarbonyl-2-phenyl-Δ¹-pyrroline 
• 84-58-2 2,3-dicyano-5,6-dichloro-p-benzoquinone 
• 623-33-6 glycine ethyl ester hydrochloride 
• 212265-33-3 ethyl 2-phenyl-1-pyrroline-5-carboxylate 1-oxide 
• 75-36-5 acetyl chloride 
• 79-03-8 propionyl chloride 
• 98-88-4 benzoyl chloride 
• 927-58-2 4-bromobutyroyl chloride 
• 516465-86-4 4,5-dibromo-1H-pyrrole-2-carboxylic acid ethyl ester 
• 98-80-6 phenylboronic acid 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 65117-56-8 α-azido-5-phenyl-2,4-pentadienoic acid ethyl ester 

Downstream Products

• 37670-55-6 ethyl 1-methyl-5-phenyl-1H-pyrrole-2-carboxylate 
• 6636-06-2 5-phenyl-1H-pyrrole-2-carboxylic acid 

Relevant academic research and scientific papers

Radical cyclisation from alkenyl oxaziridines

Some 6-oxa-1-azabicyclo[3.1.0]hexanes have been prepared by photoisomerisation of alkenyl nitrone esters and peracid oxidation of pyrrolines. Their ring-opening reactions with iron(II) sulfate, tri-n-butyl tin hydride and copper(I)triphenylphosphine chlor

Synthesis and Aromatization of Ethyl Esters of cis-4-(Methanesulfonyl)-cis-5-arylprolines. Unusual Synthesis of 5-Aryl-2-acetylpyrrole

Abstract: 1-Bromovinyl and vinyl methyl sulfones undergo 1,3-dipolar cycloaddition reactions with azomethinylides generated in situ from ethyl N-benzylideneglycinates under the action of silver acetate and triethylamine (toluene, 20°C, 48 h) to form ethyl

Cyanine-based near infra-red organic photoredox catalysis

Direct metal-free near infra-red photoredox catalysis is applied to organic oxidation, photosensitization and reduction, involving cyanines as photocatalysts. This photocatalyst is competitive with conventional reactions catalyzed under visible light. Kin

Boric acid compounds, and preparation method and use thereof

The invention relates to the fields of pharmaceutical chemistry and medicine therapeutics, concretely relates to a new boric acid compounds, and a preparation method and a use thereof, and especially relates to new substituted five-membered heterocyclic boric acid and substituted benzo five-membered boric acid compounds, and a preparation method thereof. A result of bioactive screening test of the substituted five-membered heterocyclic boric acid and substituted benzo five-membered boric acid compounds having a structure represented by a formula shown in the description shows that the compounds have a proteasome inhibition effect, and can be further used for preparing medicines for treating proteasome correlated diseases.

NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives

The 1H and 13C NMR resonances of 22 5-(5-substituted-2-nitrophenyl)-1H-pyrrole-2-carboxamides, 22 5-(5-substituted-2-aminophenyl)-1H-pyrrole-2-carboxamides, and 9 5-phenyl-1H-pyrrole-2-carboxamides we

Synthesis and radical reactions of isomeric alkenyl oxaziridines

Several alkenyl oxaziridines were prepared either by photoisomerisation of the precursor nitrones, or by peracid oxidation of the analogous pyrrolines. In each case the oxaziridines were produced as separable mixtures of diastereoisomers, and reasons for

An unusual dehalogenation in the Suzuki coupling of 4-bromopyrrole-2-carboxylates

An unusual dehalogenation of 4-bromopyrrole-2-carboxylates under Suzuki coupling conditions has been observed. This dehalogenation can be suppressed by protection of the pyrrole nitrogen. Using a BOC protecting group, not only is dehalogenation suppressed

Synthesis and reactivity of 1-pyrroline-5-carboxylate ester 1-oxides

Some C5 mono- and diester-substituted 1-pyrroline-1-oxides have been prepared via reductive cyclisation of the corresponding γ-nitro carbonyl compounds. Ethyl 2-phenyl-1-pyrroline-1-oxide-5-carboxylate 5c was regioselectively alkylated at C5. Acylation of this molecule occurs exclusively on the nitrone oxygen and leads to C3 substituted pyrrolines as the result of a hetero-Cope rearrangement. (C) 2000 Elsevier Science Ltd.

The application of vinylogous iminium salts and related synthons to the regiocontrolled preparation of 2,3- and 2,5-disubstituted pyrroles

The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles. Reactions of related three-carbon synthons with sarcosine and gly

General method for the synthesis of 5-arylpyrrole-2-carboxylic acids

5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-Δ1-pyrroline-5-carboxylate followed by basic hydrolysis.