921207-64-9

Basic information

• Product Name: 1,3-Dioxane, 2-phenyl-4-[(2R)-2-(phenylmethoxy)-4-penten-1-yl]-6-[3-(phenylmethoxy) propyl]-, (2S,4R,6S)-
• CAS NO: 921207-64-9
• Molecular Formula: C32H38O4
• Molecular Weight: 486.651
• Mol File: 921207-64-9.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane, 2-phenyl-4-[(2R)-2-(phenylmethoxy)-4-penten-1-yl]-6-[3-(phenylmethoxy) propyl]-, (2S,4R,6S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane, 2-phenyl-4-[(2R)-2-(phenylmethoxy)-4-penten-1-yl]-6-[3-(phenylmethoxy) propyl]-, (2S,4R,6S)-(921207-64-9)
• EPA Substance Registry System: 1,3-Dioxane, 2-phenyl-4-[(2R)-2-(phenylmethoxy)-4-penten-1-yl]-6-[3-(phenylmethoxy) propyl]-, (2S,4R,6S)-(921207-64-9)

Safety Data

• Hazardous Substances Data: 921207-64-9(Hazardous Substances Data)

Upstream product

• 212184-58-2 ethyl (2E,4E)-8-(benzyloxy)octa-2,4-dienoate 
• 693-02-7 hex-1-yne 
• 1002-36-4 hep-2-yn-1-ol 
• 63478-76-2 1-hydroxy-6-heptyne 
• 921207-65-0 ethyl 2-{(2S,4S,6S)-6-[3-(benzyloxy)propyl]-2-phenyl-1,3-dioxan-4-yl}acetate 
• 921207-67-2 ethyl (4S,5S)-3-[(3-benzyloxy-propyl)-2-oxo-[1,3]dioxolan-4-yl] acrylate 
• 921207-66-1 ethyl 8-benzyloxy-oct-2-ynoate 
• 565473-04-3 ((hept-6-yn-1-yloxy)methyl)benzene 
• 943768-65-8 2-(2S,4R,6S)-6-[3-(benzyloxy)propyl]-2-phenyl-1,3-dioxan-4-yl-1-ethanol 
• 921207-70-7 5-{(2S,4S,6S)-6-[3-(benzyloxy)propyl]-2-phenyl-1,3-dioxan-4-yl}-1-penten-4-one 
• 915141-48-9 2-[(2S,4S,6S)-6-(3-benzyloxy-propyl)-2-phenyl-1,3-dioxan-4-yl]acetaldehyde 
• 921207-71-8 (4R)-5-[(2S,4S,6S)-6-(3-benzyloxy-propyl)-2-phenyl-1,3-dioxan-4-yl]pent-1-en-4-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 570397-58-9 (3S,5R,7R)-7-(benzyloxy)-3-[3-(benzyloxy)propyl]-5-hydroxy-14-methoxy-3,4,5,6,7,8-hexahydro-1H-2-benzoxacyclododecin-1-one 
• 921207-73-0 methyl 2-{(1E,4R)-4-benzyloxy-5-[(2S,4R,6S)-6-(3-benzyloxy-propyl)-2-phenyl-1,3-dioxan-4-yl]pent-1-enyl}-6-methoxy-benzoate 

Relevant articles and documents

Stereoselective synthesis of a key intermediate of (-)-apicularen A

Progress towards the stereoselective formal synthesis of (-)-apicularen A is described. The convergent approach involves the assembly of aliphatic and aromatic fragments via Grubbs's cross metathesis. Other key reactions in the strategy include Sharpless

De novo formal synthesis of (-)-apicularen A via an iterative asymmetric hydration sequence

(Chemical Equation Presented) A de novo approach to the formal total synthesis of the macrolide natural product (-)-apicularen A has been achieved in 18 steps'from achiral starting materials. Both the absolute and relative stereochemistries of apicularen A were introduced by a Sharpless asymmetric dihydroxylation, a π-allyl-palladium catalyzed reduction, a stereoselective reduction, and a base-promoted transannulation to install the C-9 stereocenter.