922-17-8

Usage

InChI:InChI=1/C6H14O2/c1-3-5(7)6(8)4-2/h5-8H,3-4H2,1-2H3

Upstream product

• 82188-39-4 (3R,4R)-(+)-1,6-dibromohexane-3,4-diol 
• 1069-23-4 (3R,4R)-1,5-hexadiene-3,4-diol 
• 4437-51-8 3,4-hexanedione 
• 22520-19-0 trans-hexane-1,2-diol 
• 116297-02-0 (4S)-4-hydroxyhexan-3-one 
• 64-19-7 acetic acid 
• 123-38-6 propionaldehyde 
• 71-23-8 propan-1-ol 
• 110-82-7 cyclohexane 
• 13269-52-8 trans-3-Hexene 
• 67-63-0 isopropyl alcohol 
• 50-70-4 D-sorbitol 
• 36611-94-6 meso-(2R,3S)-2,3-diethyloxirane 
• 219527-99-8 O¹,O²,O⁵,O⁶-tetrakis-(toluene-4-sulfonyl)-D-mannitol 

Downstream Products

• 509150-88-3 (3R,4R)-4-(4-Methoxy-benzyloxy)-hexan-3-ol 
• 4437-51-8 3,4-hexanedione 
• 802294-64-0 propionic acid 
• 123-38-6 propionaldehyde 
• 4984-85-4 propioin 
• 82343-36-0 C₂₀H₂₄N₂O₄ 

Relevant academic research and scientific papers

Chromium-Catalyzed Production of Diols From Olefins

Processes for converting an olefin reactant into a diol compound are disclosed, and these processes include the steps of contacting the olefin reactant and a supported chromium catalyst comprising chromium in a hexavalent oxidation state to reduce at least a portion of the supported chromium catalyst to form a reduced chromium catalyst, and hydrolyzing the reduced chromium catalyst to form a reaction product comprising the diol compound. While being contacted, the olefin reactant and the supported chromium catalyst can be irradiated with a light beam at a wavelength in the UV-visible spectrum. Optionally, these processes can further comprise a step of calcining at least a portion of the reduced chromium catalyst to regenerate the supported chromium catalyst.

Mo–Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties

A catalytic domino reduction–imine formation–intramolecular cyclization–oxidation for the general synthesis of a wide variety of biologically relevant N-polyheterocycles, such as quinoxaline- and quinoline-fused derivatives, and phenanthridines, is reported. A simple, easily available, and environmentally friendly dioxomolybdenum(VI) complex has proven to be a highly efficient and versatile catalyst for transforming a broad range of starting nitroarenes involving several redox processes. Not only is this a sustainable, step-economical as well as air- and moisture-tolerant method, but also it is worth highlighting that the waste byproduct generated in the first step of the sequence is recycled and incorporated in the final target molecule, improving the overall synthetic efficiency. Moreover, selected indoloquinoxalines have been photophysically characterized in cyclohexane and toluene with exceptional fluorescence quantum yields above 0.7 for the alkyl derivatives.

Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716T butanediol dehydrogenase

α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716T (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn2+ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated.

Method for synthesizing o-glycol compounds by virtue of bifunctional characteristic catalyst

The invention belongs to the technical field of organic chemical synthesis and particularly relates to a method for synthesizing o-glycol compounds by virtue of a bifunctional characteristic catalyst.The o-glycol compounds are prepared from olefin and an oxidizing agent through reaction under the effect of the bifunctional characteristic catalyst, wherein the bifunctional characteristic catalystcontains the following components in percentage by mass: 25%-75% of a titanium silicalite molecular sieve, 20%-70% of nano-silicon dioxide and 5%-10% of heteropolyacid. The method provided by the invention has the beneficial effects that a process for synthesizing o-glycol by virtue of a traditional two-step method is simplified; the catalyst can still remain good catalytic performance under a long-period operation condition in the method, the raw material conversion rate is high, and the yields of the o-glycol compounds are high; and the olefin raw material conversion rate is 80.2%-94.6%, andthe selectivity of o-glycol generated through reaction is 85.7%-96.3%.

Method for synthesizing vicinal diol compound by virtue of one-step process

The invention belongs to the technical field of organic chemical synthesis, and in particular relates to a method for synthesizing a vicinal diol compound by virtue of a one-step process. The vicinaldiol compound is obtained by carrying out reaction on olefin and an oxidizing agent in presence of a bifunctional catalyst, wherein the bifunctional catalyst comprises 25-75% of titanium silicalite molecular sieves, 20-70% of nano alumina and 3-8% of boric oxide in percentage by mass with the titanium silicalite molecular sieves, nano alumina and boric oxide as the benchmarks. The method for synthesizing the vicinal diol compound has the advantages that the traditional two-step vicinal diol synthesis technology is simplified; in the synthetic method, a catalyst still maintains good catalytic performance under long-period operation condition, raw material conversion rate is high, and yield of the vicinal diol compound is high; and olefin raw material conversion rate is 80.2-94.6%, and vicinal diol reaction generation selectivity is 85.7-96.3%.

Structural Study of Bromide-Bridged Pd Chain Complex with Weak CH···O Hydrogen Bonds

A novel Br-bridged Pd chain complex, [Pd(hxn)2Br](TsO)2 (2) (TsO– = p-toluenesulfonate), was synthesized from a new in-plane ligand (3S,4S)-3,4-diaminohexane (hxn). 2 forms PdII/PdIV mixed-valence state, as confirmed by single-crystal X-ray structure analysis and polarized Raman spectra. The hxn ligand provides the additional hydrogen bonds (CH···O) between the methyl group of the ligands and the O atoms of TsO– anions, which are weaker than those observed in the chain complex with hydroxy group, [Pd(dabdOH)2Br]Br2 (1).

Method for synthesizing vicinal diol compound which takes hydrocarbon epoxide as raw material

The present invention discloses a method for preparing a vicinal diol compound which takes a hydrocarbon epoxide as a raw material. The method takes the hydrocarbon epoxide as the raw material and takes an anion exchange resin as a catalyst. The vicinal diol compound is prepared by using a fixed bed continuous hydrolysis reaction technology. The anion exchange resin is a halogen-substituted macroporous polystyrene-divinyl benzene quaternary ammonium salt type anion exchange resin. The synthesis method is simple, the catalyst can be used many times, the raw material conversion rate is high, and the yield of the vicinal diol compound is high.

Method for synthesizing ortho-diol compound by using macroporous anion exchange resin as catalyst

The invention discloses a method for synthesizing an ortho-diol compound by using macroporous anion exchange resin as a catalyst. According to the method, hydrocarbon epoxide is used as a raw material, the anion exchange resin is used as the catalyst, and a fixed bed continuous hydrolysis reaction technology is adopted for preparing the ortho-diol compound; the anion exchange resin is halogen ortho-substituted macroporous polystyrene-divinyl benzene quaternary phosphonium salt type anion exchange resin. The synthesis method is simple, the catalyst can be used repeatedly, the conversion rate of the raw material is high, and the yield of the ortho-diol compound is high.

Synthetic method for o-glycol compounds

The invention discloses a synthetic method for o-glycol compounds. The method prepares the o-glycol compounds by using a fixed-bed continuous hydrolysis reaction process with hydrocarbon epoxides as raw materials and anion exchange resin as a catalyst, wherein the anion exchange resin is halogen-p-substituted macroporous polystyrene-divinyl benzene quaternary phosphonium salt anion exchange resin. The synthetic method is simple; the catalyst can be repeatedly used a plurality of times; the conversion rate of the raw materials is high; and the yield of the o-glycol compounds is high.

Method for preparing vicinal diol compound through ring-opening reaction

The present invention discloses a method for preparing a vicinal diol compound through a ring-opening reaction. The method takes a hydrocarbons epoxide as a raw material and takes an anion exchange resin as a catalyst. The vicinal diol compound is prepared by using a fixed bed continuous hydrolysis reaction technology. The anion exchange resin is a halogen-substituted macroporous polystyrene-divinyl benzene quaternary ammonium salt type anion exchange resin. The synthesis method is simple, the catalyst can be used many times, the raw material conversion rate is high, and the yield of the vicinal diol compound is high.