4984-85-4

Basic information

• Product Name: PROPIOIN
• Synonyms: 3-Hexanone, 4-hydroxy-;3-Hydroxy-4-hexanone;Ethyl alpha-hydroxypropyl ketone;4-HYDROXY-3-HEXANONE;PROPIONOIN;PROPIOIN;TIMTEC-BB SBB008173;4-hydroxyhexan-3-one
• CAS NO: 4984-85-4
• Molecular Formula: C₆H₁₂O₂
• Molecular Weight: 116.16
• EINECS: 225-637-3
• Mol File: 4984-85-4.mol
• Article Data: 26

Chemical Properties

• Melting Point: -3.75°C (estimate)
• Boiling Point: 167 °C
• Flash Point: 54 °C
• Appearance: /
• Density: 0,95 g/cm3
• Vapor Pressure: 0.701mmHg at 25°C
• Refractive Index: 1.4340 (589.3 nm 21℃)
• PKA: 13.03±0.20(Predicted)
• CAS DataBase Reference: PROPIOIN(CAS DataBase Reference)
• NIST Chemistry Reference: PROPIOIN(4984-85-4)
• EPA Substance Registry System: PROPIOIN(4984-85-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22-10
• Safety Statements: 26-36/37/39-36/37
• RIDADR: UN 1993C 3 / PGIII
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 4984-85-4(Hazardous Substances Data)

Usage

General Description

"Propionin" seems to be a misspelled term and there is no notable chemical substance known specifically by this name. A potentially related term, "Propionin", is not recognized in the chemistry field. However, a potentially related compound that's well-known is "Propionin acid" also known as "propanoic acid". This is a naturally occurring carboxylic acid that is a common component in human and animal metabolism. It's frequently used as a food preservative and as an ingredient in fragrances and cosmetics. It's also used in agriculture, for animal feed and for crop-protection purposes.

InChI:InChI=1/C6H12O2/c1-3-5(7)6(8)4-2/h5,7H,3-4H2,1-2H3

Upstream product

• 105-37-3 Ethyl propionate 
• 67-64-1 acetone 
• 589-38-8 n-hexan-3-one 
• 6802-75-1 diethyl isopropylidenemalonate 
• 123-38-6 propionaldehyde 
• 922-17-8 hexane-3,4-diol 
• 64-19-7 acetic acid 
• 71-43-2 benzene 
• 75-07-0 acetaldehyde 
• 123-72-8 butyraldehyde 
• 100-52-7 benzaldehyde 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 22520-39-4 (3S,4R)-hexane-3,4-diol 

Downstream Products

• 73673-27-5 4,5-diethyl-1H-imidazole 
• 4437-51-8 3,4-hexanedione 
• 123-38-6 propionaldehyde 
• 13461-41-1 diethylene glycol monosalicylate 
• 25044-01-3 2-methyl-pent-1-en-3-one 
• 2497-21-4 4-hexen-3-one 
• 1352457-21-6 2-phenyl-3-ethoxycarbonyl-4,5-diethylfuran 
• 1352438-95-9 C₁₃H₁₈O₄S 
• 105955-86-0 4,5-diethyl-thiazol-2-ylamine 
• 439145-77-4 2-amino-4,5-diethyloxazole 
• 39081-91-9 2,5-dibromo-3,4-hexanedione 
• 4437-52-9 diethylglyoxime 
• 130-79-0 Diethylstilbestrol dimethyl ether 
• 53190-59-3 4-cyclohexyl-hexan-3-one 

Relevant articles and documents

Reaction of dialkylmagnesium with carbon monoxide. II

Reaction of MgEt2 with CO gives Et2CO, Et2CHOH, EtCOCH(OH)Et, EtCOCHEt2 and EtCOC(OH)Et2.The qualitative and quantitative composition of the product mixture was found to be dependent on the MgEt2 concentration and the polarity of solvent.The kinetic results reveal that reaction of CO with MgEt2 and with its dissociation product MgEt3-, followed by the formation of the Et2CO and EtCOCHEt2, respectively.The other compounds are formed in the subsequent reactions.The rate constants of formation of pentanone-3 and 4-ethylhexanone-3 are equal k1 0.292 s-1 and k2 0.450 s-1, respectively.

Sol-gel synthesis of ceria-zirconia-based high-entropy oxides as high-promotion catalysts for the synthesis of 1,2-diketones from aldehyde

Efficient Lewis-acid-catalyzed direct conversion of aldehydes to 1,2-diketones in the liquid phase was enabled by using newly designed and developed ceria–zirconia-based high-entropy oxides (HEOs) as the actual catalysts. The synergistic effect of various cations incorporated in the same oxide structure (framework) was partially responsible for the efficiency of multicationic materials compared to the corresponding single-cation oxide forms. Furthermore, a clear, linear relationship between the Lewis acidity and the catalytic activity of the HEOs was observed. Due to the developed strategy, exclusively diketone-selective, recyclable, versatile heterogeneous catalytic transformation of aldehydes can be realized under mild reaction conditions.

Preparation Method for 2,3-pentanedione

A preparation method for 2,3-pentanedione, including the steps of adding one or both of 3-hydroxy-2-pentanone and 2-hydroxy-3-pentanone into water and conducting mixing, and introducing ozone at the temperature of 3-20° C. for a reaction to obtain 2,3-pentanedione. The synthesis process of the present invention uses ozone for oxidizing a mixture containing 3-hydroxy-2-pentanone and 2-hydroxy-3-pentanone, acetic acid is used as a cocatalyst, reaction conditions are mild, the operation process is simple, the product yield is high, and the cost is low.

Synthesizing method of 3,4-heptadione

The invention provides a synthesizing method of 3,4-heptadione. The synthesizing method comprises the following steps of (1) using propionaldehyde and butyraldehyde as raw materials, adding a main catalyst, and reacting under the alkaline condition, so as to synthesize 4-hydroxyl-3-heptanone; (2) mixing the 4-hydroxyl-3-heptanone, sulfuric acid and an oxidant to oxidize, so as to obtain the 3,4-heptadione. The synthesizing method of the 3,4-heptadione has the advantages that the main raw materials are the propionaldehyde and butyraldehyde, the obtaining of the raw materials is easy, the cost is low, and the production cost is reduced.