925463-53-2

Upstream product

• 925463-43-0 4-amino-3-benzyloxy-phenol 
• 221615-94-7 3-(benzyloxy)-4-nitrophenol 
• 925463-44-1 N-(2-benzyloxy-4-hydroxy-phenyl)-4-methyl-benzenesulfonamide 
• 925463-49-6 N-(2-benzyloxy-4-hydroxy-5,8-bis-methoxymethoxymethyl-5,8-dihydro-naphthalen-1-yl)-4-methyl-benzenesulfonamide 
• 925463-51-0 trifluoro-methanesulfonic acid 3-benzyloxy-5,8-bis-methoxymethoxymethyl-4-(toluene-4-sulfonylamino)-5,8-dihydro-naphthalen-1-yl ester 
• 107550-83-4 (2E,4E)-hexa-2,4-diene-1,6-diol 
• 446-36-6 5-fluoro-2-nitrophenol 
• 100-39-0 benzyl bromide 
• 129464-01-3 2-(benzyloxy)-4-fluoro-1-nitrobenzene 

Downstream Products

• 925463-58-7 trifluoro-methanesulfonic acid 4-(2-benzylamino-1-methoxymethoxymethyl-ethyl)-7-benzyloxy-3-methoxymethoxymethyl-1-(toluene-4-sulfonyl)-1H-indol-5-yl ester 
• 1026943-43-0 5-benzyloxy-1,8-bis-methoxymethoxymethyl-6-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-3,6-diaza-as-indacene 
• 925463-59-8 3-benzyl-5-benzyloxy-1,8-bis-methoxymethoxymethyl-6-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-3,6-diaza-as-indacene 
• 925463-55-4 trifluoro-methanesulfonic acid 7-benzyloxy-4-(2-methoxycarbonyloxy-1-methoxymethoxymethyl-ethyl)-3-methoxymethoxymethyl-1-(toluene-4-sulfonyl)-1H-indol-5-yl ester 

Relevant academic research and scientific papers

Aryl amidation routes to dihydropyrrolo[3,2-e]indoles and pyrrolo[3,2-f]tetrahydroquinolines: Total synthesis of the (±)-CC-1065 CPI subunit

CC-1065 and the related duocarmycins are members of a structurally unique family of naturally occurring molecules and remain some of the most rigorously studied antitumor compounds to date. Herein we describe a total synthesis of the (±)-CC-1065 CPI subun