92863-34-8

Basic information

• Product Name: 4-CYCLOHEXYL-BENZOIC ACID METHYL ESTER
• Synonyms: METHYL 4-CYCLOHEXYLBENZOATE;4-CYCLOHEXYL-BENZOIC ACID METHYL ESTER;Cyclohexyl benzoic acid methyl ester;Benzoic acid, 4-cyclohexyl-, methyl ester
• CAS NO: 92863-34-8
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.29
• Mol File: 92863-34-8.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 323.632°C at 760 mmHg
• Flash Point: 144.708°C
• Appearance: /
• Density: 1.047g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CYCLOHEXYL-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYCLOHEXYL-BENZOIC ACID METHYL ESTER(92863-34-8)
• EPA Substance Registry System: 4-CYCLOHEXYL-BENZOIC ACID METHYL ESTER(92863-34-8)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 92863-34-8(Hazardous Substances Data)

Usage

Description

4-Cyclohexyl-benzoic acid methyl ester, with the chemical formula C14H18O2, is a methyl ester of 4-cyclohexylbenzoic acid. It is a white or off-white solid that is known for its distinct properties and potential applications across various industries.

Uses

Used in Flavor and Fragrance Industry:
4-Cyclohexyl-benzoic acid methyl ester is used as a flavoring or fragrance ingredient in various products, such as perfumes and cosmetics. Its unique scent profile makes it a valuable addition to these formulations, enhancing the sensory experience for consumers.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 4-cyclohexyl-benzoic acid methyl ester may have potential applications in the pharmaceutical industry. Given its chemical structure, it could potentially be utilized in the development of new drugs or as an intermediate in the synthesis of pharmaceutical compounds.
Used in Agricultural Industry:
Similarly, the potential applications of 4-cyclohexyl-benzoic acid methyl ester in the agricultural industry are not detailed in the materials. However, it could be explored for use in the development of agrochemicals, such as pesticides or herbicides, due to its chemical properties.
Safety Precautions:
As with any chemical, it is important to exercise caution when handling and using 4-cyclohexyl-benzoic acid methyl ester. Proper safety precautions should be followed to minimize potential risks, ensuring the well-being of both individuals and the environment.

InChI:InChI=1/C14H18O2/c1-16-14(15)13-9-7-12(8-10-13)11-5-3-2-4-6-11/h7-11H,2-6H2,1H3

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 446065-11-8 cyclohexyltrifluoro-λ⁴-borane potassium salt 
• 108-85-0 1-bromocyclohexane 
• 372-46-3 fluorocyclohexane 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 695-12-5 vinylcyclohexane 
• 110-82-7 cyclohexane 
• 626-62-0 Cyclohexyl iodide 
• 720-75-2 methyl 4-phenylbenzoate 
• 110-83-8 cyclohexene 
• 108-91-8 cyclohexylamine 
• 436799-32-5 5-bromo-2(trifluoromethyl)pyridine 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 931-51-1 cyclohexylmagnesiumchloride 

Downstream Products

• 191287-05-5 4-cyclohexyl-3-nitrobenzoic acid methyl ester 
• 252552-35-5 1-(4-cyclohexylphenyl)-2,2,2-trifluoroethan-1-one 
• 1456602-25-7 diethyl 4-(N-(4-cyclohexylbenzyl)-4-phenoxybenzamido)benzylphosphonate 
• 1456602-26-8 diethyl 3-(N-(4-cyclohexylbenzyl)-4-phenoxybenzamido)benzylphosphonate 
• 1456602-24-6 diethyl 3-(N-(4-cyclohexylbenzyl)-4-phenoxybenzamido)phenylphosphonate 
• 1456602-23-5 diethyl 4-(N-(4-cyclohexylbenzyl)-4-phenoxybenzamido)phenylphosphonate 
• 111818-33-8 1-(bromomethyl)-4-cyclohexylbenzene 
• 1367608-58-9 4-cyclohexylbenzyl(triphenyl)phosphonium bromide 

Relevant articles and documents

Enabling Metallophotoredox Catalysis in Parallel Solution-Phase Synthesis Using Disintegrating Reagent Tablets

Compressed tablets containing a mixture of a photocatalyst, a nickel catalyst, an inorganic base, and an inert excipient are employed as a fast, safe, and user-friendly chemical delivery system for two different metallophotoredox-catalyzed reactions. This delivery method simplifies the preparation of compound libraries using photoredox chemistry in a parallel setting. The reagent tablets were successfully applied to late-stage functionalization of drug-like intermediates. These tablets can be prepared with various reagents and catalysts in different sizes and be stored on the bench thanks to blister packaging.

Dealkenylative Ni-Catalyzed Cross-Coupling Enabled by Tetrazine and Photoexcitation

A new and general method to functionalize the C(sp3)-C(sp2) bond of alkyl and alkene linkages has been developed, leading to the dealkenylative generation of carbon-centered radicals that can be intercepted to undergo Ni-catalyzed C(sp3)-C(sp2) cross-coupling. This one-pot protocol leverages the easily procured alkene feedstocks for organic synthesis with excellent functional group compatibility without the need for a photoredox catalyst.

Micelle enabled C(sp2)-C(sp3) cross-electrophile coupling in waterviasynergistic nickel and copper catalysis

A robust and sustainable C(sp2)-C(sp3) cross-electrophile coupling was developedvianickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.