93-29-8Relevant articles and documents
One-pot hydroformylation/O-acylation of propenylbenzenes for the synthesis of polyfunctionalized fragrances
Delolo, Fábio G.,Vieira, Gabriel M.,Villarreal, Jesus A.A.,dos Santos, Eduardo N.,Gusevskaya, Elena V.
, p. 272 - 279 (2020/06/17)
A process involving the hydroformylation/O-acylation of propenylbenzenes with a phenolic group is described for eugenol, isoeugenol, chavicol, propenyl guaethol, 2-allylphenol, and 2-allyl-6-methylphenol. The reactions occur in parallel, under the same reaction conditions in anisole, a solvent with an impressive sustainability rank comparable to those of ethanol and water. The products contain formyl and acetoxy moieties, both established olfactory groups in flavor and fragrance industry, and present potential as new fragrance components with less allergenic properties. To the best of our knowledge, this is the first time that a one-pot process involving hydroformylation combined with further functionalization in a remote site is described.
Method for synthesizing E-methyl styrene compound
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Page/Page column 7, (2020/03/25)
The method for preparing E-pyridyl or alkyl-substituted,bipyridine, in a solvent, in the presence of nitrogen protection, in, reaction 0 °C -50 °C in the presence of a metal nickel salt 24 - 36h, ligand and an additive is E, and the preparation method disclosed by the invention has the advantages, cheap 2,2 ’ - raw materials, easiness in obtaining 2,2 ’ - and the like. The ligand is,bipyridine or an alkyl-substituted bipyridyl compound, in the. presence of a nitrogen, protection agent, in a solvent.
Free Radical Scavenging Activity of Essential Oil of Eugenia caryophylata from Amboina Island and Derivatives of Eugenol
Julianus Sohilait, Hanoch,Kainama, Healthy
, p. 422 - 428 (2019/08/01)
Essential oil from Eugenia caryophylata was normally used to heal many different deseaces. Various chemical compositions of essential oil distilled and steamed of Moluccas Eugenia caryophylata has been investigated by many different researchers. Even though an intensive research has been carried out of the local chemotypes, a very detail study has not been fully investigated to find out the complete chemical compounds from the plant essential oil and its content associated with their biological activities. In present paper, we assess the free radical scavenging of E. caryophylata collected from Moluccas islands, Indonesia. Essential oil was extracted from leaves, buds, and stems of plant by steam distillation and analyzed using GC-FID and GC-MS. The result showed that free radical activity of essential oil, main constituent and its derivatives were analized using in vitro method. Essential oil activity from stem obtained as (0.82±0.15 μg/mL) was higher than that from bud and leaf possessing both 1,1-diphenyl-2-picrylhydrazyl (DPPH) and (2,2'-azino-bis-3-ethylbenzthizoline-6-sulphonic acid (ABTS) radical scavenging assays by sinergism of eugenol, eugenyl acetate, β-caryophylene and humulene. The activity of isoeugenol (2) (3.59±0.54 μM) and (5.0±0.53 μM) scavenging DPPH and ABTS, respectively, as derivatives eugenol was higher than (3), (4) and (5). Although (6) was active originally, it was inactive after conversion of the ester. While the change of the double bond of location to conjungation structure caused more activity scavenging radicals than the starting molecule.
