930-61-0

Basic information

• Product Name: 2,4-DIMETHYL-2-IMIDAZOLINE
• Synonyms: 4,5-dihydro-2,4-dimethyl-1h-imidazol;2,4-DIMETHYL-2-IMIDAZOLINE;4,5-dihydro-2,4-dimethyl-1H-imidazole;2,5-dimethyl-4,5-dihydro-1H-imidazole;1H-IMidazole, 4,5-dihydro-2,4-diMethyl-
• CAS NO: 930-61-0
• Molecular Formula: C₅H₁₀N₂
• Molecular Weight: 98.15
• EINECS: 213-220-9
• Mol File: 930-61-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 198.6°Cat760mmHg
• Flash Point: 73.9°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.504mmHg at 25°C
• Refractive Index: 1.4806
• PKA: 11.04±0.70(Predicted)
• CAS DataBase Reference: 2,4-DIMETHYL-2-IMIDAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHYL-2-IMIDAZOLINE(930-61-0)
• EPA Substance Registry System: 2,4-DIMETHYL-2-IMIDAZOLINE(930-61-0)

Safety Data

• Statements: 36/38
• Safety Statements: 26-36
• TSCA: Yes
• Hazardous Substances Data: 930-61-0(Hazardous Substances Data)

Usage

General Description

2,4-DIMETHYL-2-IMIDAZOLINE, also known as xylazine, is a potent alpha-2 adrenergic agonist that is primarily used as a veterinary sedative and analgesic. It is commonly used in combination with ketamine to induce sedation and analgesia in animals, particularly in species such as horses, cattle, and deer. Xylazine works by acting on receptors in the central nervous system, causing sedation, muscle relaxation, and anesthetic effects. However, it also possesses analgesic properties, making it useful for both sedation and pain management in animals. Xylazine should only be used under the supervision of a veterinarian due to its potential for serious adverse effects, including respiratory depression, bradycardia, and hypotension.

InChI:InChI=1/C5H10N2/c1-4-3-6-5(2)7-4/h4H,3H2,1-2H3,(H,6,7)

Upstream product

• 127-09-3 sodium acetate 
• 123-86-4 acetic acid butyl ester 
• 78-90-0 1,2-diaminopropan 
• 35397-63-8 1-methyl-2-(methylcarbonylamino)ethylamine 
• 534-26-9 lysidine 

Downstream Products

• 250691-17-9 N-methyl-N-[2-(N'-methylamino)-2-methylethyl]acetamide 
• 353739-57-8 N-methyl-N-[2-(N'-methylamino)-1-methylethyl]acetamide 
• 14331-54-5 2,4-dimethylpyrimidine 
• 123-32-0 2,5-dimethyl-pyrazine 
• 4472-45-1 4-chloro-2,6-dimethylpyrimidine 
• 108-50-9 2,6-dimethylpyrazine 
• 4994-86-9 4-chloro-2-methylpyrimidine 
• 693-98-1 2-methylimidazole 
• 930-62-1 2,4-Dimethylimidazole 
• 75712-73-1 5-Chloro-2,4-dimethylpyrimidine 
• 5053-43-0 2-methylpyrimidine 
• 95-58-9 2-chloro-3-methylpyrazine 
• 95-89-6 2,5-dimethyl-3-chloropyrazine 
• 38557-72-1 2-chloro-3,5-dimethylpyrazine 

Relevant articles and documents

METHOD FOR PRODUCING IMIDAZOLINE COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing an imidazoline compound having high yield and small amount of impurity. SOLUTION: There is provided a method for producing an imidazoline compound (B) using a diamine monoamide compound (A) represented by the general formula (1), wherein the method includes a dehydration condensation step of the diamine monoamide compound (A) and a distillation step of the imidazoline compound (B). In the dehydration condensation step, the temperature of the dehydration condensation reaction of (A) is 100°C to 160°C in a time of 50% or more of the process time from when the conversion rate from (A) to (B) becomes 55% until when the conversion rate from (A) to (B) becomes 70%, and a the gas-phase pressure at the temperature of the dehydration condensation reaction of (A) is P1 which satisfies the conditions 1. In the distillation step, the temperature of the liquid containing (A) and (B) is 100°C to 190°C in a time of 50% or more of the process time from when 30 wt.% of the total distillate of (B) is distillated until when 90 wt.% of the total distillate of (B) is distillated, and a pressure (B) in the gas-phase of the distillation step is P2 which satisfies the condition 2. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

1,2- and 1,3-Diamine Exchange between Substituted 4,5-Dihydroimidazoles and 1,4,5,6-Tetrahydropyrimidines: Routes to Benzimidazoles, Dihydroimidazoles, and Tetrahydropyrimidines

A range of 2-substituted 4,5-dihydroimidazoles and 2-substituted 1,4,5,6-tetrahydropyrimidines when heated with an excess of substituted ethane-1,2-diamines, o-phenylenediamines, and propane-1,3-diamine underwent diamine exchange to give 2-substituted heterocycles derived from the solvent diamine.The reaction was an equilibrium process favouring six-membered rings.The synthetic scope is amplified by the ready aromatisation of these partially reduced heterocycles.