934-87-2Relevant articles and documents
Organocatalytic enantioselective decarboxylative addition of malonic half thioesters to imines
Ricci, Alfredo,Pettersen, Daniel,Bernardi, Luca,Fini, Francesco,Fochi, Mariafrancesca,Herrera, Raquel Perez,Sgarzani, Valentina
, p. 1037 - 1040 (2007)
We describe a biomimetic organocatalytic enantioselective decarboxylative addition of malonic acid half thioesters to imines. This simple protocol makes use of readily available Cinchona-derived organocatalysts and nucleophiles at the carboxylate oxidation state. The resulting β-amino thioesters, being attractive precursors for the preparation of optically active, β-amino acids, are formed in good yields and in up to 79 % ee. As suggested by several mechanistic insights the desired products are formed via initial formation of a thioester acetate enolate via decarboxylation of the malonic acid half thioester, followed by addition to the imine.
Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same
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Page/Page column 39-41, (2021/08/04)
Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed.
Manganese(iii)-promoted thiocarbonylation of alkylborates with disulfides: synthesis of aliphatic thioesters
Chen, Bo,Wu, Xiao-Feng
supporting information, p. 9654 - 9658 (2021/12/01)
A Mn(iii)-promoted thiocarbonylation procedure toward the synthesis of thioesters has been developed. By employing easily available disulfides and potassium alkyltrifluoroborates as the starting materials, and cheap and non-toxic Mn(OAc)3·2H2O as the promotor, a broad range of thioesters were synthesized in good to excellent yieldsviaradical intermediates.
