93841-86-2

Basic information

• Product Name: (-)-N-(1-R-Ethoxycarbonxyl-3-phenylpropyl)-L-alanine, Benzyl Ester
• Synonyms: (-)-N-(1-R-Ethoxycarbonxyl-3-phenylpropyl)-L-alanine, Benzyl Ester;(αR)-α-[[(1S)-1-Methyl-2-oxo-2-(phenylMethoxy)ethyl]aMino]benzenebutanoic Acid Ethyl Ester
• CAS NO: 93841-86-2
• Molecular Formula: C₂₂H₂₇NO₄
• Molecular Weight: 369.45408
• Product Categories: Amino Acids & Derivatives;Aromatics;Chiral Reagents;Intermediates
• Mol File: 93841-86-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 487.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.114±0.06 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane
• PKA: 4.54±0.39(Predicted)
• CAS DataBase Reference: (-)-N-(1-R-Ethoxycarbonxyl-3-phenylpropyl)-L-alanine, Benzyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-N-(1-R-Ethoxycarbonxyl-3-phenylpropyl)-L-alanine, Benzyl Ester(93841-86-2)
• EPA Substance Registry System: (-)-N-(1-R-Ethoxycarbonxyl-3-phenylpropyl)-L-alanine, Benzyl Ester(93841-86-2)

Safety Data

• Hazardous Substances Data: 93841-86-2(Hazardous Substances Data)

Upstream product

• 1117-96-0 Diazoethan 
• 710-11-2 2-oxo-4-phenylbutyric acid 
• 5557-81-3 L-alanine benzyl ester hydrochloride 
• 100-39-0 benzyl bromide 
• 64920-29-2 2-oxo-4-phenylbutanoic acid ethyl ester 
• 46460-23-5 ethyl 2-amino-4-phenyl-(2S)-butyrate 
• 93836-48-7 (S)-2-(trifluoromethanesulphonyloxy)propionic acid benzyl ester 
• 16503-46-1 2-bromo-4-phenyl butanoic acid 
• 5440-40-4 2-(acetylamino)-4-phenylbutanoic acid 
• 1012-05-1 D,L-homophenylalanine 
• 100-51-6 benzyl alcohol 
• 82795-51-5 D-homophenylalanine 
• 943-73-7 D-homophenylalanine 
• 56777-24-3 benzyl (S)-Lactate 

Downstream Products

• 111542-00-8 (S)-2-((R)-1-Benzyloxycarbonyl-ethylamino)-4-phenyl-butyric acid ethyl ester; hydrochloride 
• 130316-66-4 (2S)-3-aza-4-(ethoxycarbonyl)-2-methyl-6-phenylhexanamide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 117605-22-8 (S)-3-[(R)-2-((S)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester 
• 89371-34-6 (S)-2-[(R)-1-(2,5-Dioxo-pyrrolidin-1-yloxycarbonyl)-ethylamino]-4-phenyl-butyric acid ethyl ester 
• 85196-26-5 (2R)-2-amino>propionic acid 
• 117605-19-3 (4S)-3-<(2R)-2-amino>propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylic acid 
• 117560-16-4 (R)-2-((S)-1-Benzyloxycarbonyl-ethylamino)-4-phenyl-butyric acid ethyl ester; hydrochloride 
• 84324-12-9 N-<1(R)-(ethoxycarbonyl)-3-phenylpropyl>-(S)-alanine 
• 877932-98-4 N-(1-ethoxycarbonyl-3-phenylpropyl)-L-alanine 

Relevant articles and documents

On the synthesis and analysis of R,S- and S,R-N-[1-(ethoxycarbonyl)-3-phenylpropyl]-alanine

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Ophthalmic compositions

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A Stereoselective Synthesis of N--L-alanine Derivatives by Means of Reductive Amination

A stereoselective synthesis of N--L-alanine, a portion of the molecule of angiotensin converting-enzyme(ACE) inhibitors, by reductive amination utilizing catecholborane and further applications of the reaction to the synthesis of ACE inhibitors are described.