124044-66-2 Usage
Description
D-Homophenylalanine ethyl ester is a chemical compound that belongs to the class of homophenylalanines, which are analogs of the amino acid phenylalanine. It is an ethyl ester derivative of D-homophenylalanine, characterized by its unique structure and properties. D-Homophenylalanine ethyl ester is commonly used as a building block in the synthesis of peptide and protein-based pharmaceuticals, making it a valuable reagent in the development of potential therapeutic agents and drug candidates. Its importance lies in the field of medicinal chemistry and drug discovery, where it contributes to the creation of bioactive compounds and potential treatments for various disease conditions.
Uses
Used in Pharmaceutical Synthesis:
D-Homophenylalanine ethyl ester is used as a building block for the synthesis of peptide and protein-based pharmaceuticals. Its unique structure allows for the development of potential therapeutic agents and drug candidates, particularly in the field of medicinal chemistry and drug discovery.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, D-Homophenylalanine ethyl ester is utilized as a reagent for the synthesis of various bioactive compounds. Its properties make it suitable for creating potential drug candidates targeting different disease conditions, thus contributing to the advancement of drug discovery.
Used in Drug Discovery:
D-Homophenylalanine ethyl ester plays a crucial role in drug discovery, where it aids in the development of new pharmaceuticals. Its unique structure and properties enable the synthesis of compounds with potential therapeutic effects, broadening the scope of treatment options for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 124044-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,0,4 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 124044-66:
(8*1)+(7*2)+(6*4)+(5*0)+(4*4)+(3*4)+(2*6)+(1*6)=92
92 % 10 = 2
So 124044-66-2 is a valid CAS Registry Number.
124044-66-2Relevant articles and documents
Asymmetric Synthesis of N-Substituted α-Amino Esters from α-Ketoesters via Imine Reductase-Catalyzed Reductive Amination
Yao, Peiyuan,Marshall, James R.,Xu, Zefei,Lim, Jesmine,Charnock, Simon J.,Zhu, Dunming,Turner, Nicholas J.
supporting information, p. 8717 - 8721 (2021/03/16)
N-Substituted α-amino esters are widely used as chiral intermediates in a range of pharmaceuticals. Here we report the enantioselective biocatalyic synthesis of N-substituted α-amino esters through the direct reductive coupling of α-ketoesters and amines employing sequence diverse metagenomic imine reductases (IREDs). Both enantiomers of N-substituted α-amino esters were obtained with high conversion and excellent enantioselectivity under mild reaction conditions. In addition >20 different preparative scale transformations were performed highlighting the scalability of this system.
IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS
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Page/Page column 64, (2018/11/22)
The present invention is in the field of bioluminescence in biology and/or medicine. In particular, the invention provides imidazopyrazine derivatives, processes for preparation thereof, and their uses as luciferins.
Copper-Catalyzed Addition of Alkylboranes to Iminoacetates: Access to α-Alkyl Branched α-Amino Acids
Xiao, Xinsheng,Zhang, Wei,Lu, Xiaoxia,Deng, Yuanfu,Jiang, Huangfeng,Zeng, Wei
, p. 2497 - 2509 (2016/08/16)
A copper(I)-catalyzed addition of alkylborane reagents to α-iminoacetates has been developed to assemble both acyclic and cyclic α-branched α-amino carboxylic acid derivatives in good yields. A wide variety of unactivated alkenes are well tolerated in this transformation. (Figure presented.).