944329-19-5Relevant articles and documents
Efficient synthesis from d-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-l-arabinitol LABNAc, a potent pyrrolidine inhibitor of hexosaminidases
Rountree, J.S.Shane,Butters, Terry D.,Wormald, Mark R.,Dwek, Raymond A.,Asano, Naoki,Ikeda, Kyoko,Evinson, Emma L.,Nash, Robert J.,Fleet, George W.J.
, p. 4287 - 4291 (2008/02/12)
The synthesis from d-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-l-arabinitol LABNAc proceeded in an overall yield of 25%; the enantiomer, 2-acetamido-1,4-imino-1,2,4-trideoxy-d-arabinitol DABNAc, was prepared from l-lyxonolactone. LABNAc and N-