96013-56-8

Basic information

• Product Name: 2-Piperidinone, 4-methyl-1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 96013-56-8
• Molecular Formula: C13H17NO3S
• Molecular Weight: 267.349
• Mol File: 96013-56-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Piperidinone, 4-methyl-1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone, 4-methyl-1-[(4-methylphenyl)sulfonyl]-(96013-56-8)
• EPA Substance Registry System: 2-Piperidinone, 4-methyl-1-[(4-methylphenyl)sulfonyl]-(96013-56-8)

Safety Data

• Hazardous Substances Data: 96013-56-8(Hazardous Substances Data)

Upstream product

• 104375-65-7 4-methyl-N-(3-methylpent-4-en-1-yl)benzenesulfonamide 
• 96013-55-7 1-[(4-methylphenyl)sulfonyl]-5,6-dihydro-1H-piperidin-2-one 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 51174-44-8 3-methyl-4-penten-1-ol 
• 1257867-21-2 3-methyl-N-tosylpyrrolidine-2-carbaldehyde 
• 1257867-34-7 (3-methyl-N-tosylpyrrolidin-2-yl)methanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 626-58-4 4-methylpiperidin 
• 23438-61-1 1-(toluene-4-sulfonyl)piperidin-2-one 
• 675-20-7 piperidin-2-one 
• 75-16-1 methylmagnesium bromide 
• 60212-39-7 4-methyl-1-tosylpiperidine 
• 917-64-6 methyl magnesium iodide 

Downstream Products

• 626232-87-9 trifluoromethanesulfonic acid 4-methyl-1-(toluene-4-sulfonyl)-1,4,5,6-tetrahydropyridin-2-yl ester 
• 317339-77-8 4-methyl-1-tosyl-5,6-dihydropyridin-2(1H)-one 
• 626232-96-0 6-(1-ethoxybuta-1,3-dienyl)-4-methyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydropyridine 
• 646996-64-7 1-[4-methyl-1-(toluene-4-sulfonyl)-1,4,5,6-tetrahydropyridin-2-yl]cyclobutanol 

Relevant articles and documents

Platinum-Catalyzed Desaturation of Lactams, Ketones, and Lactones

The development of a general platinum-catalyzed desaturation of N-protected lactams, ketones, and lactones to their conjugated α,β-unsaturated counterparts is reported. The reaction operates under mildly acidic conditions at room temperature or 50 °C. It is scalable and tolerates a wide range of functional groups. The complementary reactivity to the palladium-catalyzed desaturation is demonstrated in the efficient conversion of iodide, bromide, and sulfur-containing substrates.

Synthesis of functionalized 1-azaspirocyclic cyclopentanones using bronsted acid or N-bromosuccinimide promoted ring expansions

Azaspirocyclic ring systems are present in a variety of alkaloids. Functionalized 1-azaspirocyclopentanones (6, 7, 11, 12) can be efficiently constructed through semipinacol ring expansion reactions of 2-(1- hydroxycyclobutyl)-p-toluenesulfonylenamides (4

CONJUGATE ADDITION OF ORGANOCOPPER REAGENTS TO N-TOSYLATED α, β-UNSATURATED AMIDES

N-Tosylated α, β-unsaturated amides and lactams undergo facile conjugate addition with R2CuLi or RMgX/CuI (cat.).Stereoselective synthesis of trans-β,γ-dialkyl-γ-lactams can be achieved by this procedure.The resulting N-tosylamide moiety is further transformed to alcohol and several carbonyl compounds by way of reduction or nucleophillic displacement.