96881-37-7

Basic information

• Product Name: 1H-Imidazo[1,2-a]purine-7-carboxaldehyde, 4,9-dihydro-4,6-dimethyl-9-oxo-1-(phenylmethyl)-
• CAS NO: 96881-37-7
• Molecular Formula: C17H15N5O2
• Molecular Weight: 321.338
• Mol File: 96881-37-7.mol

Chemical Properties

• CAS DataBase Reference: 1H-Imidazo[1,2-a]purine-7-carboxaldehyde, 4,9-dihydro-4,6-dimethyl-9-oxo-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazo[1,2-a]purine-7-carboxaldehyde, 4,9-dihydro-4,6-dimethyl-9-oxo-1-(phenylmethyl)-(96881-37-7)
• EPA Substance Registry System: 1H-Imidazo[1,2-a]purine-7-carboxaldehyde, 4,9-dihydro-4,6-dimethyl-9-oxo-1-(phenylmethyl)-(96881-37-7)

Safety Data

• Hazardous Substances Data: 96881-37-7(Hazardous Substances Data)

Upstream product

• 65120-81-2 1-benzyl-4,6-dimethyl-1,4-dihydro-imidazo[1,2-a]purin-9-one 
• 68-12-2 N,N-dimethyl-formamide 
• 124927-18-0 <(1-benzyl-4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo<1,2-a>purin-7-yl)methyl>triphenylphosphonium bromide 
• 96881-38-8 1-benzyl-1,4-dihydro-7-hydroxymethyl-4,6-dimethyl-9H-imidazo<1,2-a>purin-9-one 
• 2958-98-7 3-methylguanine 
• 100-39-0 benzyl bromide 
• 65120-78-7 7-benzyl-3-methylguanine 
• 110691-69-5 (R^*,R^*)-1-benzyl-1,4-dihydro-7-(1,2-dihydroxy-3-methylbutyl)-4,6-dimethyl-9H-imidazo-<1,2-a>purin-9-one 
• 79-37-8 oxalyl dichloride 
• 124910-11-8 (E)-1-benzyl-1,4-dihydro-4,6-dimethyl-7-(3-methyl-1-butenyl)-9H-imidazo<1,2-a>purin-9-one 

Downstream Products

• 96854-31-8 -4-<1-Benzyl-4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo<1,2-a>purin-7-yl>-2-<(methoxycarbonyl)amino>-3-butenoic Acid Methyl Ester 
• 35693-91-5 wybutine 
• 110691-69-5 (R*,S*)-1-benzyl-1,4-dihydro-7-(1,2-dihydroxy-3-methylbutyl)-4,6-dimethyl-9H-imidazo<1,2-a>purin-9-one 
• 110691-72-0 1-benzyl-1,4-dihydro-4,6-dimethyl-7-(3-methylbutyl)-9H-imidazo<1,2-a>purin-9-one 
• 214117-24-5 (+/-)-1-benzyl-α-<(methoxycarbonyl)amino>-β-oxo-4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo<1,2-a>purine-7-butanoic acid methyl ester 
• 70363-52-9 (R*,S*)-β-hydroxy-α-<(methoxycarbonyl)amino>-4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo<1,2-a>purine-7-butanoic acid methyl ester 
• 70363-52-9 (R*,R*)-β-hydroxy-α-<(methoxycarbonyl)amino>-4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo<1,2-a>purine-7-butanoic acid methyl ester 
• 110658-45-2 <4R-<4α(S^*),5β>>-5-<1-benzyl-4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo<1,2-a>purin-7-yl>-α-<(methoxycarbonyl)amino>-2-oxo-1,3-dioxolane-4-acetic acid methyl ester 
• 110582-31-5 <4S-<4α(R^*),5β>>-5-<1-benzyl-4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo<1,2-a>purin-7-yl>-α-<(methoxycarbonyl)amino>-2-oxo-1,3-dioxolane-4-acetic acid methyl ester 
• 110658-44-1 αS-(αR^*,βS^*,γS^*)-1benzyl-4,9-dihydro-β,γ-dihydroxy-α-<(methoxycarbonyl)amino>-4,6-dimethyl-9-oxo-1H-imidazo<1,2-a>purine-7-butanoic acid methyl ester 
• 110582-30-4 <αS-(αR^*,βR^*,γR^*)>-1-benzyl-4,9-dihydro-β,γ-dihydroxy-α-<(methoxycarbonyl)amino>-4,6-dimethyl-9-oxo-1H-imidazol<1,2-a>purine-7-butanoic acid methyl ester 
• 136978-28-4 (S)-(E)-(1-benzyl-4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo<1,2-a>purin-7-yl)-2-<(methoxycarbonyl)amino>but-3-enoic acid 
• 136978-29-5 1-Benzyl-6-[(E)-2-(1-benzyl-4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo[1,2-a]purin-7-yl)-vinyl]-4-methyl-9-oxo-4,9-dihydro-1H-imidazo[1,2-a]purine-7-carbaldehyde 
• 96881-39-9 7-methylwye 

Relevant articles and documents

Synthesis of β-hydroxywybutines, the most probable alternatives for the hypermodified base of rat liver phenylalanine transfer ribonucleic acid

Deoxygenation of the 1,2-glycol (±)-5 was achieved at the position adjacent to the heterocycle through the cyclic carbonate (±)-14, providing the monohydroxy compound 6. This new method of regioselective deoxygenation was employed for the first synthesis

Studies towards the synthesis of the fluorescent bases of phenylalanine transfer ribonucleic acids: synthesis of 7-methylwye isolated from extremely thermophilic archaebacteria.

Acid- or base-catalyzed acylation of 1-benzylwye (7) provided the 7-substituted derivatives 9, 10, and 11 in poor yields. Although the reactions of lithiated 7 with electrophiles gave the 2-substituted derivatives 14, 15, 17, 20, 21, and 22, lithiation of

ACCESS TO THE SYNTHESIS OF WYBUTOSINE, THE FIRST TRICYCLIC FLUORESCENT NUCLEOSIDE ISOLATED FROM PHENYLALANINE TRANSFER RIBONUCLEIC ACIDS

An improved synthesis of the key intermediate 5 for the chiral syntheses of wybutine (1c) and hydroxywybutine (1d) has been achieved by palladium-catalyzed vinylation, which has been utilized for the first synthesis of 3-β-D-ribofuranosylwybutine (2c).

SYNTHESIS OF (S)-(-)-WYBUTINE, THE FLUORESCENT MINOR BASE FROM YEAST PHENYLALANINE TRANSFER RIBONUCLEIC ACIDS

The Wittig reaction of 1-benzyl-7-formylwye (12) with (R)-ethyl>triphenylphosphonium chlorid (8) followed by successive methylation and reduction gave (-)-wybutine .