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98737-29-2

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  • 1-Benzyl-2, 3-Epoxy N-Propyl-carbamic AcidTert-Butyl Ester

    Cas No: 98737-29-2

  • No Data

  • 1 Metric Ton

  • 1 million Metric Ton/Year

  • COLORCOM LTD.
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98737-29-2 Usage

Chemical Properties

Off-White Solid

Uses

It function as a building block employed in the synthesis of HIV-1 protease inhibitors and is also employed in synthesizing (hydroxyethyl)urea peptidomimetrics and arylsulfonamides possessing anti-HIV activity. It is a Enantiomer S. Atazanavir intermediate.

Check Digit Verification of cas no

The CAS Registry Mumber 98737-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,7,3 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 98737-29:
(7*9)+(6*8)+(5*7)+(4*3)+(3*7)+(2*2)+(1*9)=192
192 % 10 = 2
So 98737-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H21NO3/c1-15(2,3)19-14(17)16-12(13-10-18-13)9-11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,16,17)/t12-,13-/m0/s1

98737-29-2 Well-known Company Product Price

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  • TCI America

  • (E0893)  (2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane  >98.0%(GC)

  • 98737-29-2

  • 1g

  • 590.00CNY

  • Detail
  • TCI America

  • (E0893)  (2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane  >98.0%(GC)

  • 98737-29-2

  • 5g

  • 1,680.00CNY

  • Detail
  • Alfa Aesar

  • (H56001)  (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98%   

  • 98737-29-2

  • 250mg

  • 560.0CNY

  • Detail
  • Alfa Aesar

  • (H56001)  (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98%   

  • 98737-29-2

  • 1g

  • 1568.0CNY

  • Detail
  • Alfa Aesar

  • (H56001)  (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98%   

  • 98737-29-2

  • 5g

  • 4599.0CNY

  • Detail
  • Aldrich

  • (476951)  (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane  99%

  • 98737-29-2

  • 476951-1G

  • 2,577.51CNY

  • Detail
  • Aldrich

  • (476951)  (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane  99%

  • 98737-29-2

  • 476951-5G

  • 8,482.50CNY

  • Detail

98737-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane

1.2 Other means of identification

Product number -
Other names (2S,3S)-N-t-Boc-3-amino-1,2-epoxy-4-phenylbutane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98737-29-2 SDS

98737-29-2Downstream Products

98737-29-2Relevant articles and documents

Synthesis method of (2S, 3S)-3-(t-butyloxycarboryl amino)-1, 2-epoxy-4-phenylbutane

-

, (2021/06/23)

The invention relates to the technical field of synthesis of drug intermediates, in particular to a synthesis method of (2S, 3S)-3-(t-butyloxycarboryl amino)-1, 2-epoxy-4-phenylbutane. The method comprises the following steps: condensing N-t-butyloxycarboryl-L-phenylalanine serving as a raw material with substituted phenol under the action of a condensing agent to obtain active ester 15; reacting the active ester 15 with a ylide reagent and alkali to obtain a sulfoxide ylide intermediate 16; reacting the sulfoxide ylide intermediate 16 with halide salt under the action of a catalyst to obtain a halogenated ketone intermediate 6; reducing the halogenated ketone intermediate 6 through a reducing agent under the action of a catalyst to obtain a halogenated methanol intermediate 7; and removing halogen acid from the halogenated methanol intermediate 7 under the action of alkali, and carrying out condensation cyclization to obtain the target product (2S, 3S)-3-(t-butyloxycarboryl amino)-1, 2-epoxy-4-phenylbutane. The synthesis method of the (2S, 3S)-3-(t-butyloxycarboryl amino)-1, 2-epoxy-4-phenylbutane, provided by the invention, has the characteristics of cheap and easily available initial raw materials, safe and controllable process and easiness in operation.

Continuous production method of benzoic acid derivative

-

Paragraph 0032-0033; 0035, (2021/11/14)

The invention relates to the technical field of preparation of benzoic acid derivatives. The invention particularly relates to a continuous production method of a benzoic acid derivative. The continuous reaction device is characterized by comprising a small-diameter sleeve, wherein the small-diameter sleeve is sleeved with a large-diameter sleeve, and a small pipeline is arranged between the small-diameter sleeve and the large-diameter sleeve, and a plurality of small holes are arranged on the small pipeline. The small-diameter casing is rotated, the large-diameter casing is fixed, and the reaction liquid composed of the nitric acid and the toluene derivative is between a small-diameter casing pipe and a large-diameter casing pipe.

Bimetallic oxide nanoparticles confined in ZIF-67-derived carbon for highly selective oxidation of saturated C–H bond in alkyl arenes

Huang, Cheng,Su, Xiaoyan,Gu, Xiangyu,Liu, Rui,Zhu, Hongjun

, (2020/10/15)

Zeolite imidazolate frameworks (ZIFs) have recently emerged as an ideal type of carbon precursors with abundant tailorability. In this work, a series of ZIF-derived porous carbon catalysts have been prepared with encapsulation of bimetallic oxide nanoparticles via simple thermal treatment. The composition and structure of these catalysts were confirmed in detail by different characterization methods. The bimetallic oxide (Mn/Co, Fe/Co, and Cu/Co) nanoparticles were encapsulated in the nitrogen-doped graphitized carbon matrix. Moreover, the hierarchically porous structure and carbon defects were successfully constructed in the carbon catalysts. Additionally, in the selective oxidation of saturated C–H bonds in alkyl arenes, the carbon catalysts demonstrate outstanding performance for the oxidation of C–H bonds to corresponding carboxyl groups. This was due to their unique structure can greatly promote mass transfer and molecular oxygen activation, resulting in high conversion and high selectivity. Remarkably, this work here could also provide a novel strategy to the controllable synthesis of metal–organic frameworks (MOFs)-derived carbon catalysts for enhanced performance in heterogeneous catalysis.

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