98974-04-0

Basic information

• Product Name: (4R)-4-Ethyl-2-oxazolidinone
• Synonyms: (4R)-4-Ethyl-2-oxazolidinone
• CAS NO: 98974-04-0
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13046
• Mol File: 98974-04-0.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 298.9 °C at 760 mmHg
• Flash Point: 134.5 °C
• Appearance: /
• Density: 1.047 g/cm³
• Vapor Pressure: 0.00124mmHg at 25°C
• Refractive Index: 1.427
• CAS DataBase Reference: (4R)-4-Ethyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-Ethyl-2-oxazolidinone(98974-04-0)
• EPA Substance Registry System: (4R)-4-Ethyl-2-oxazolidinone(98974-04-0)

Safety Data

• Hazardous Substances Data: 98974-04-0(Hazardous Substances Data)

Usage

General Description

(4R)-4-Ethyl-2-oxazolidinone is a chemical compound with a molecular formula of C5H9NO2. It is an oxazolidinone derivative, which is a class of compounds that has various biological activities and applications. This particular compound is a chiral molecule, meaning it has a non-superimposable mirror image. (4R)-4-Ethyl-2-oxazolidinone has been studied for its potential as a solvent, as a building block in organic synthesis, and as a starting material for the synthesis of pharmaceuticals and other compounds. It also has the potential to be used in asymmetric catalysis and other chemical reactions due to its chiral nature.

InChI:InChI=1/C5H9NO2/c1-2-4-3-8-5(7)6-4/h4H,2-3H2,1H3,(H,6,7)/t4-/m1/s1

Upstream product

• 96-20-8 2-aminobutanol 
• 105-58-8 Diethyl carbonate 
• 75-44-5 phosgene 
• 1659-31-0 2,2'-dipyridyl carbonate 
• 13997-20-1 4-ethyl-1,3-oxazolidine-2-thione 
• 592-35-8 butyl carbamate 
• 201230-82-2 carbon monoxide 
• 13973-23-4 2--1-butanol 
• 2549-67-9 2-ethylaziridine 
• 124-38-9 carbon dioxide 
• 57-13-6 urea 
• 530-62-1 1,1'-carbonyldiimidazole 
• 5856-63-3 (2R)-2-aminobutan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 5467-84-5 1,3-diphenethylurea 
• 1466-67-7 1,3-dibenzylurea 
• 100317-12-2 N-benzyl-N'-(1-hydroxymethyl-propyl)-urea 
• 6744-64-5 N,N'-dibenzhydryl-urea 
• 101785-47-1 N-benzhydryl-N'-(1-hydroxymethyl-propyl)-urea 
• 1296671-51-6 3-(3-(3,4,5-Trimethoxyphenyl)prop-1-(E)-enyl)-4-(R)-ethyloxazolidin-2-one 
• 1296671-53-8 (2R,3R,4S)-3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(3,4-dimethoxyphenyl)-2-((R)-4-ethyl-2-oxo-oxazolidin-3-yl)-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 1296671-54-9 (2R,3R,4S)-3-(3,4,5-trimethoxybenzyl)-4-(3,4,5-trimethoxyphenyl)-2-((R)-4-ethyl-2-oxo-oxazolidin-3-yl)-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 1296671-55-0 (2R,3R,4S)-4-(benzo[d][1,3]dioxol-5-yl)-3-(3,4,5-trimethoxybenzyl)-2-((R)-4-ethyl-2-oxo-oxazolidin-3-yl)-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 1296671-56-1 (2R,3R,4S)-4-(3,4-dimethoxyphenyl)-3-(3,4,5-trimethoxybenzyl)-2-((R)-4-ethyl-2-oxo-oxazolidin-3-yl)-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 1502-22-3 2-(1-cyclohexenyl)cyclohexanone 
• 1172623-40-3 (R)-3-cyclohexenyl-4-ethyloxazolidin-2-one 
• 725257-88-5 (2R,4R)-2-[(4R)-4-ethyl-2-oxo-1,3-oxazolidin-3-yl]-4-phenyl-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 634916-95-3 (4R)-4-ethyl-3-vinyl-oxazolidin-2-one 

Relevant articles and documents

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

1H-PYRAZOLO[4,3-B]PYRIDINES AS PDE1 INHIBITORS

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Synthesis of some 2-Oxazolidinones in mild conditions

One step efficient protocol for the synthesis of 2-oxazolidinones in paste chemical medium is described under microwave activation with 80 % yield.