99432-86-7

Upstream product

• 70150-56-0 (+/-)-4-hydroxy-4-methyl-2-cyclohexen-1-one 
• 100-66-3 methoxybenzene 
• 333-27-7 methyl trifluoromethanesulfonate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 191725-57-2 1-methoxy-4-(1-methoxyprop-1-en-2-yl)benzene 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 99432-87-8 (3S,4S)-4-(4-Methoxy-phenyl)-4-methyl-3-vinyl-cyclohexanone 
• 99432-87-8 (3R^*,4S^*)-4-(4-methoxyphenyl)-4-methyl-3-vinylcyclohexan-1-one 
• 1220126-45-3 (S)-4'-methoxy-1-methyl-2,3-dihydro[1,1'-biphenyl]-4(1H)-one 
• 60393-95-5 (R)-4'-methoxy-1-methyl-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one 
• 1643565-89-2 diethyl 2-((1S,2R)-4'-methoxy-1-methyl-4-oxo-1,2,3,4-tetrahydro-[1,1'-biphenyl]-2-yl)malonate 
• 1643566-05-5 diethyl 2-((1R,2R)-4'-methoxy-1-methyl-4-oxo-1,2,3,4-tetrahydro-[1,1'-biphenyl]-2-yl)malonate 
• 1643566-27-1 4'-methoxy-1-methyl-[1,1'-biphenyl]-4(1H)-one 
• 99432-92-5 (3R^*,4S^*)-3-carboxymethyl-4-(4-hydroxyphenyl)-4-methylcyclohexan-1-one 
• 99432-89-0 (3R^*,4S^*)-4-(4-methoxyphenyl)-4-methyl-3-vinylcyclohexan-1-one ethylene acetal 
• 99432-93-6 (3R^*,4S^*)-4-(acetoxyphenyl)-3-carboxymethyl-4-methylcyclohexane-1-one 
• 99432-94-7 Acetic acid 4-((1S,2R)-2-chlorocarbonylmethyl-1-methyl-4-oxo-cyclohexyl)-phenyl ester 
• 99432-90-3 (3R^*,4S^*)-3-(2-hydroxyethyl)-4-(4-methoxyphenyl)-4-methylcyclohexan-1-one ethylene acetal 
• 99432-91-4 (3R^*,4S^*)-3-(carboxymethyl)-4-(4-methoxyphenyl)-4-methylcyclohexan-1-one 

Relevant academic research and scientific papers

Nickel-Catalyzed Desymmetric Hydrogenation of Cyclohexadienones: An Efficient Approach to All-Carbon Quaternary Stereocenters

Nickel-catalyzed desymmetric hydrogenation has been achieved. With the Ni(OTf)2/(S,S)-Ph-BPE system, a series of ?,?-disubstituted cyclohexadienones were transformed to the corresponding cyclohexenones with a chiral all-carbon quaternary center at the γposition in high yields (92-98%) and excellent enantioselectivities (92%-99% ee). This catalytic system can also tolerate the desymmetric reaction of spirocarbocyclic cyclohexadienones to produce the corresponding cyclohexenones bearing a chiral spiro quaternary carbon with high yields (94%-98%) and ee values (96%-99% ee). Furthermore, this methodology provides an efficient and concise synthetic route to the intermediate of natural products cannabispirenones A and B.

Asymmetric Synthesis of Remote Quaternary Centers by Copper-Catalyzed Desymmetrization: An Enantioselective Total Synthesis of (+)-Mesembrine

Catalytic asymmetric syntheses of remote quaternary stereocenters have been developed by copper-catalyzed 1,4-hydrosilylation of ?,?-disubstituted cyclohexadienones. A variety of cyclohexenones have been synthesized in good yield and excellent enantioselectivity. Versatile 2-silyloxy diene intermediates bearing ?,?-disubstituted all carbon stereogenic centers can be isolated from the mild reaction conditions. The utility of this strategy is exemplified in a catalytic asymmetric total synthesis of (+)-mesembrine.

Asymmetric Induction at Remote Quaternary Centers of Cyclohexadienones by Rhodium-Catalyzed Conjugate Hydrosilylation

The enantioselective desymmetrizing conjugate hydrosilylation of prochiral differently γ,γ-disubstituted cyclohexadienone derivatives 2 to furnish the corresponding cyclohexenones 4 with a remote chiral all-carbon quaternary center at the γ position is de

Novel synthesis of 2-aryl or 4-arylcyclohexenones

In anhydrous HF, 4-hydroxy-4-methylcyclohex-2-en-1-one 5 reacts with aromatics (benzene, toluene, anisole, para-bromoanisole) to yield 2 and 4 arylated ketones.Reaction with benzene yields enone 2 (73percent).With toluene, reaction affords enone 6 (24perc

Synthesis of 4-alkyl-4-(4-methoxyphenyl)cyclohex-2-en-1-ones and 5-alkyl-5-phenyl-1,3-cyclohexadienes from bis(tricarbonylchromium)-coordinated biphenyls

(η6:η6-Biphenyl)[Cr(CO)3] 2 and (η6η64,4'-dimethoxybiphenyl) [Cr(CO)3]2 were chemically reduced with lithium anthracenide or lithium naphthalenide in THF to generate s