99540-20-2

Usage

Uses

Used in Organic Synthesis:
2-(2-IODO-5-METHOXY-PHENYL)-N,N-DIMETHYL-ACETAMIDE is used as a synthetic intermediate for the preparation of various organic compounds. Its presence in reactions can facilitate the formation of desired products through its reactivity and the influence of its functional groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(2-IODO-5-METHOXY-PHENYL)-N,N-DIMETHYL-ACETAMIDE is utilized as a building block for the development of new drugs. Its unique chemical properties allow it to be incorporated into the molecular structures of potential therapeutic agents, contributing to their pharmacological profiles.
Used in Chemical Research:
2-(2-IODO-5-METHOXY-PHENYL)-N,N-DIMETHYL-ACETAMIDE is also employed in chemical research as a model compound to study reaction mechanisms and to explore new synthetic methodologies. Its reactivity and structural features make it an interesting subject for academic and industrial research endeavors.

Upstream product

• 79-37-8 oxalyl dichloride 
• 73029-52-4 2-(2-iodo-5-methoxyphenyl)acetic acid 
• 90526-08-2 2-(3-methoxyphenyl)-N,N-dimethylacetamide 
• 124-40-3 dimethyl amine 
• 112399-38-9 (2-Iodo-5-methoxy-phenyl)-acetyl chloride 

Downstream Products

• 99540-37-1 2-iodo-5-methoxy-N,N-dimethylbenzeneethanamine 
• 698357-92-5 2-[(2',6'-dichlorophenyl)amino]-5-methoxyphenyl-N,N-dimethylacetamide 
• 99540-38-2 2-iodo-5-methoxy-N,N-dimethylbenzeneethanamine hydrochloride 
• 99540-02-0 5-methoxy-N,N-dimethyl-2-(phenylethynyl)benzeneethanamine 
• 698357-97-0 2-[(2',6'-dichlorophenyl)amino]-5-hydroxyphenyl-N,N-dimethylacetamide 
• 69002-84-2 2-(2-((2,6-dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid 

Relevant academic research and scientific papers

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac

In humans, metabolism of the commonly used nonsteroidal antiinflammatory drug diclofenac 1 yields principally the 4′-hydroxy 2, 5-hydroxy 3, and acyl glucuronide 4 metabolites. All three metabolites have been implicated in rare idiosyncratic adverse react

Methods for the treatment of hypertension

Acetylene compounds of the formula (I): STR1 wherein Y, R1, R2, R3, and R4 are as described herein, m is 0-3, n is 0-2 and Ar is phenyl or an aromatic heterocycle are disclosed. The compounds possess antihyperte

Acetylene amines and their use as vasodilators and antihypertensives

Acetylenes of the following formula (I): STR1 wherein Y, m, R1, R2, R3, n and R4 are defined herein and R5 is hydrogen, alkyl, cycloalkyl or substituted alkyl are useful vasodilators and antihypertens

2-Ethynylbenzenealkanamines. A new class of calcium entry blockers

A series of 2-(aryl- or alkylethynyl)benzenealkanamines were synthesized. They exhibit antihypertensive activity in spontaneously hypertensive rats and coronary vasodilator activity with minimal negative inotropic activity in the 'Langendorff' guinea pig heart in vitro. They have been shown to exert their activity by inhibition of Ca2+ influx across cell membranes. Optimal activity is found among the N-(arylethyl)-5-methoxy-α-methyl-2-(phenylethynyl)benzeneethanamines and -propanamines.