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gamma-Valerolactone

  • Name gamma-Valerolactone
  • EINECS203-569-5
  • CAS No. 108-29-2
  • Density1.05 g/cm3
  • PSA26.30000
  • LogP0.71190
  • Solubilitymiscible with water
  • Melting Point-31 °C(lit.)
  • FormulaC5H8O2
  • Boiling Point206.624 °C at 760 mmHg
  • Molecular Weight100.117
  • Flash Point74.98 °C
  • Transport InformationN/A
  • Appearancecolorless to pale yellow clear liquid
  • Safety39-26
  • Risk Codes36
  • Molecular Structure
    Molecular Structure of 108-29-2 (gamma-Valerolactone)
  • Hazard SymbolsIrritantXi
  • SynonymsIrritantXi
  • Article Data466

gamma-Valerolactone Chemical Properties

Molecular Formula:C5H8O2
Molar mass:100.11582g/mol
Structure:
          
Synonyms :4-Pentanolide;Valerolactone;gamma-Valerolakton;gamma-Pentanolactone;.gamma.-Pentalactone;Pentanolide-1,4;gamma-Valeryllactone;gamma-Valerolactone;gamma-Pentalactone
Appearance:Colorless to pale yellow transparent liquid
Density:1.04 g/cm3                                   
Flash Point:75 °C                    
Boiling Point:206.6 °C at 760 mmHg
Vapour Pressure:0.235 mmHg at 25°C           
Melting point:-31 °C(lit.)
Solubility:Immiscible in water and most organic solvents, resin, wax, etc., do not dissolve in anhydrous glycerin, gum arabic, casein and soy protein.
Water solubility:MISCIBLE
vapor density:3.45 (vs air)

gamma-Valerolactone Uses

VALEROLACTONE(108-29-2) has strong ability to respond.
VALEROLACTONE(108-29-2) can be used as resins solvents and a variety of  the compounds' intermediates . And also used as lubricants, plasticizers, non-ionic surface active agent of the gelling agent, the inner esters of lead in gasoline additives, used for dyeing cellulose esters and synthetic fibers.

gamma-Valerolactone Production

VALEROLACTONE(108-29-2) has been derived by heating acetyl-acetic acid and sulfuric acid.And also can be derived from levulinic acid on the presence of hydrogenation in the nickel, copper or other metal catalysts.

gamma-Valerolactone Toxicity Data With Reference

1.   

skn-rbt 500 mg/24H MLD

   FCTOD7    Food and Chemical Toxicology. 20 (Suppl)(1982),847.
2.   

sln-smc 24400 ppm

   MUREAV    Mutation Research. 201 (1988),431.
3.   

orl-rat LD50:8800 mg/kg

   JIHTAB    Journal of Industrial Hygiene and Toxicology. 27 (1945),263.
4.   

orl-rbt LD50:2480 mg/kg

   JIHTAB    Journal of Industrial Hygiene and Toxicology. 27 (1945),263.
5.    Carcinogenicity:4-VALEROLACTONE(108-29-2)- Not listed as a carcinogen by  NTP, IARC,ACGIH, or CA Prop 65. 
Other: See actual entry in RTECS for complete information.

gamma-Valerolactone Consensus Reports

Reported in EPA TSCA Inventory.

gamma-Valerolactone Safety Profile

Moderately toxic by ingestion. A skin irritant. Mutation data reported. Combustible liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:Xi
Risk Statements:
36:  Irritating to the eyes
Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
39:  Wear eye/face protection

gamma-Valerolactone Specification

Stability and Reactivity of 4-VALEROLACTONE(108-29-2):
Conditions to Avoid:Incompatible materials.  
Incompatibilities with Other Materials:Strong oxidizing agents.
Hazardous Decomposition Products: carbon dioxide,carbon monoxide.
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