OIL RED O (cas 14288-70-1) Is a Useful Tool to Assess Donor Liver Steatosis on Frozen Sections During Transplantation

Add time:07/18/2019    Source:sciencedirect.com

OIL RED O (cas 14288-70-1) is a useful tool to assess donor liver steatosis on frozen sections during transplantation.Steatosis is a frequent finding in liver evaluation during transplantation, accounting for 9% to 26% of biopsied donor liver. The degree of macrovesicular steatosis is classified as mild, moderate, and severe; the latter is considered an absolute contraindication to liver transplantation because it is associated with poor allograft outcome. Because of the scarcity of organs, there is a debate whether livers with less severe macrovesicular steatosis are still suitable for transplant. Consequently, tools or methods that allow a more accurate intraoperative assessment of steatosis on frozen sections are mandatory.The aim of this study is to improve intraoperative evaluation of steatosis during transplantation using Oil Red O stain on liver biopsies.

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