An efficient method for the construction of 2-Aminothiazolo[5,4-c]pyridines via K3[Fe(CN)6] oxidized SP2 CH Functionalization

Add time:07/19/2019    Source:sciencedirect.com

A practical approach to synthesize 2-aminothiazolo[5,4-c]pyridines from simple asymmetric pyridylthioureas was achieved by utilizing K3[Fe(CN)6] as the oxidant. These reactions went through an intramolecular oxidation and finally led to the formation of CS bond. Furthermore, the possible oxidative cyclization mechanism was also explored by the addition of radical scavengers, which showed that the oxidative cyclization was promoted via a free radical mechanism.

We also recommend Trading Suppliers and Manufacturers of 2-PYRIDYLTHIOUREA (cas 14294-11-2). Pls Click Website Link as below: cas 14294-11-2 suppliers

Prev:Preparation of ruthenium (III) ion-imprinted beads based on 2-PYRIDYLTHIOUREA (cas 14294-11-2) modified chitosan
Next:Structural studies of N-2-(6-aminopyridine)-N′-arylthioureas)