Cobaloxime template reactions I. The formation of N-nitrosamines

Add time:07/21/2019    Source:sciencedirect.com

The synthesis of a potent carcinogen, N-nitroso-N-methylaniline, employing a bis(dimethylglyoximato)cobaltate template is described. Carbon bonded N-methyleneaniline adducts of cobaloxime with pyridine, NO-2 or CN- in the basal (sixth) coordination position of the cobalt atom were prepared and isolated. These cobaloxime methyleneaniline adducts were found to readily undergo nitrosation when treated with nitrous acid. The resulting N-nitrosamine adducts were characterized by IR, NMR and mass spectroscopy. Interesting trans effects of the basal substituents are noted. Final template reaction products were identified by thermal degradation and chemical cleavage with Cr2+.

We also recommend Trading Suppliers and Manufacturers of N-methyleneaniline (cas 100-62-9). Pls Click Website Link as below: cas 100-62-9 suppliers

Prev:Adsorption and thermal decomposition of N-methylaniline on Pt(1 1 1)
Next:Fe/La/Zn nanocomposite with graphene oxide for photodegradation of Phenylhydrazine (cas 100-63-0))