Synthesis of 4′-cyanothymidine (cas 116195-58-5) and analogs as potent inhibitors of HIV.

Add time:07/19/2019    Source:sciencedirect.com

4′-Cyanothymidine inhibits HIV in A301 (Alex) cells with an IC50 of 0.002 μM. The uridine and cytidine analogs show similiar potencies.

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