Separation of 1-(4-tert.-butylphenyl)-4-(4-hydroxypiperidinyl)-butan-1-one and its O-alkylated isomer by capillary zone electrophoresis
-
Add time:07/19/2019 Source:sciencedirect.com
This paper describes the development and the validation of a capillary zone electrophoresis (CZE) method for the separation of position isomers: 1-(4-tert.-butylphenyl)-4-(4-hydroxypiperidinyl)-butan-1-one (hydroxybutyridine) and 1-(4-tert.-butyphenyl)-4-(piperidin-4-yloxy)-butan-1-one (O- (O-alkylated compound). In order to fix the optimum buffer pH the theoretical estimation of pka is used. Rapid and efficient separation is shown with very low detection and quantification limits and excellent detection linearity. Good values of precision and accuracy were obtained as well as ruggedness and robustness.
We also recommend Trading Suppliers and Manufacturers of 4-(4-TERT-BUTYLPHENYL)-THIOSEMICARBAZIDE (cas 109509-79-7). Pls Click Website Link as below: cas 109509-79-7 suppliers
Prev:Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay
Next:U0126 (cas 109511-58-2) attenuates ischemia/reperfusion-induced apoptosis and autophagy in myocardium through MEK/ERK/EGR-1 pathway) - 【Back】【Close 】【Print】【Add to favorite 】