A stereospecific synthesis of a renin inhibitor (BW-175) which incorporates a sulfonemethylene isostere and a dihydroxyethylene isostere.
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Add time:07/21/2019 Source:sciencedirect.com
(2S, 3R, 4S)-4-[L-N-[(2S)-3-ethylsulfonyl-2-(1-naphthylmethyl) propionyl]norleucyl]amino-5-cyclohexyl-1-morpholino-2,3-pentanediol(BW-175) was synthesized stereospecifically.
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