Synthesis, characterization and resolution of racemic (2-methylsulfinyl)phenylphosphonic acid methyl ester via its cinchoninium salts

Add time:07/20/2019    Source:sciencedirect.com

The synthesis of new (2-methylsulfinyl)phenylphosphonic acid methyl and dimethyl esters in both racemic and non-racemic forms is reported. Resolution of the racemic phosphonic acid mono-ester 1 was accomplished via diastereomeric salt formation with cinchonine. The absolute stereochemistry of the phosphonic ester products was deduced from asymmetric sulfoxidation experiments and confirmed by chemical correlation with (S)-(−)-2-methylsulfinylaniline.

We also recommend Trading Suppliers and Manufacturers of [[1-Methyl-2-(methylsulfinyl)-1H-imidazol-5-yl]methylene]propanedioic acid dimethyl ester (cas 105956-07-8). Pls Click Website Link as below: cas 105956-07-8 suppliers

Prev:Evaluation of chicken freshness using a low-cost colorimetric sensor array with AdaBoost–OLDA (cas 105955-11-1) classification algorithm
Next:A convenient route to the phosphorus and sulfur stereoisomers of ethyl menthyl (methylsulfinyl)methylphosphonate)