Inhibition of human leukocyte elastase. 6. Inhibition by 6-substituted penicillin esters.

Add time:07/11/2019    Source:sciencedirect.com

Penicillin esters substituted at C-6 with a variety of functionalities are reported as human leukocyte elastase (HLE) inhibitors. The structure activity relations for the esters and C-6 derivatives are discussed and compared to the known cephalosporin structures.

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