Radical ring opening reaction of pyridine fused heterocycles with IBA-N3 catalyzed by tetra-n-butylammonium iodide

Add time:07/20/2019    Source:sciencedirect.com

A mild, metal-free and efficient synthesis of 2,3-disubstituted acrylonitriles and α-iminonitriles through radical ring opening reaction of pyridine fused heterocycles has been developed. The tetra-n-butylammonium iodide catalyst acts as a formal one-electron donor. Compared to the previous methods, which require excessive amounts of highly explosive azide sources and the addition of oxidants, this is a safe and convenient transformation.

We also recommend Trading Suppliers and Manufacturers of 4-(3-BROMOPYRIDIN-5-YL)PYRIDINE (cas 106047-38-5). Pls Click Website Link as below: cas 106047-38-5 suppliers

Prev:Ruthenium tris bipyridine derivatives and their photocatalytic activity in [4 + 2] cycloadditions. An experimental and DFT study
Next:Design, synthesis and characterization of picoline based organoselenium compounds, 1,2-bis(pyridine-2/3/4-yl)methyl diselanes: X-ray crystal structure of 1,2-bis(pyridine-3-yl)methyldiselane)