First synthetic approach towards K-259-2, a unique calmodulin antagonist

Add time:07/20/2019    Source:sciencedirect.com

K-259-2, a unique calmodulin antagonist, is an allyl chain containing anthraquinone natural product. A regiospecific synthetic approach towards K-259-2 is herein represented. The study also showcases a protocol for synthesizing heavily substituted bromo naphthoate which was found to be suitable for fabricating the K-259-2 motif.

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