A novel rearrangement reaction conversion of 3-(chloromethyl)azetidin-2-ones to azetidine-3-carboxylic acid esters

Add time:07/11/2019    Source:sciencedirect.com

Transformation of 3-(chloromethyl)azetidin-2-ones to azetidine-3-carboxylic acid esters is described. The readily available 3-(chloromethyl)azetidin-2-ones rearranged in good yields to azetidine-3-carboxylic acid esters on treatment with alkoxides. An alternative ring opening - ring closure procedure is also identified.

We also recommend Trading Suppliers and Manufacturers of 3-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)-1,2,4-OXADIAZOLE (cas 287917-57-1). Pls Click Website Link as below: cas 287917-57-1 suppliers

Prev:Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties
Next:Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors)