Convenient access to bis-indole alkaloids. Application to the synthesis of topsentins
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Add time:07/22/2019 Source:sciencedirect.com
Topsentins and related bis-indole alkaloids may be efficiently synthesized through an addition/oxidation sequence leading to 2-(3-indolylcarbonyl)-imidazole derivatives followed by a Pd-catalyzed heteroarylation with the appropriate 3-stannylindoles.
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