Pd-catalyzed oxidative acylation of 2-phenoxypyridines with alcohols via C–H bond activation

Add time:07/22/2019    Source:sciencedirect.com

A palladium-catalyzed oxidative acylation of 2-phenoxypyridines with benzylic and aliphatic alcohols via C–H bond activation is described. This protocol represents direct access to biologically active ortho-acylphenol derivatives, and provides new opportunities to use readily available alcohols as starting materials for catalytic acylation reactions.

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