Bi(NO3)3·5H2O: An efficient catalyst for one-pot synthesis of 3-((aryl)(diethylamino)methyl)-4-hydroxy-2H-chromen-2-ones and biscoumarin derivatives

Add time:07/23/2019    Source:sciencedirect.com

An efficient one-pot synthesis of 3-((aryl)(diethylamino)methyl)-4-hydroxy-2H-chromen-2-one derivatives has been developed from diethyl amine, aromatic aldehyde and 4-hydroxy coumarin via Mannich type reaction in the presence of Bi(NO3)3·5H2O. Also, the reaction of arylaldehyde, 4-hydroxy coumarin, guanidine or acetamide in the presence of Bi(NO3)3·5H2O lead to biscoumarin derivatives and guanidine or acetamide remained unchanged.

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