Scammonins VII and VIII, two resin glycosides from Convolvulus scammonia

Add time:07/22/2019    Source:sciencedirect.com

Two minor ether-soluble resin glycosides, scamrnonins VII and VIII, were isolated from Radix Scammoniae, the roots of Convolvulus scammonia. In addition to (2S)-2-methylbutyric acid and tiglic acid, they are composed, respectively, of orizabic acid A and a new glycosidic acid named scammonic acid B, with similar macrocyclic ester structures to those of the scammonic acid A-based scammonins I–VI. Isolation of genuine scammonins III–V, which were previously obtained as peracetates, is also described.

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