6-Substituted-6-dehydro-17-alkylprogesterones: Highly active oral progestins

Add time:07/22/2019    Source:sciencedirect.com

The preparation of a series of 6-chloro-6-dehydro-17-alkylprogesterones, of the 6-fluoro and 6-methyl derivatives of 6-dehydro-17-ethylprogesterone and of 6-chloro-1,6-bisdehydroprogesterone is described. The oral progestational activity of these and other 17-alkyl-progesterone derivatives is discussed.

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