Two useful methods for the preparation of (R)- and (S)-N-methyl-1-phenyl-2-(1-pyrrolidinyl)ethanamine

Add time:07/23/2019    Source:sciencedirect.com

Two methods for the efficient preparation of either enantiomer of the synthetically useful diamine N-methyl-1-phenyl-2-(1-pyrrolidinyl)ethanamine are reported. Each of the methods starts from readily available materials (styrene oxide or phenylglycinol) and is simple, high yielding and shorter than previous synthetic routes.

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