Isolation of the tachykinin, Des[Ser1Pro2] scyliorhinin II (cas 112748-19-3) from the intestine of the ray, Torpedo marmorata

Add time:07/23/2019    Source:sciencedirect.com

A peptide with neurokinin A-like immunoreactivity was isolated from an extract of the intestine of an elasmobranch fish, Torpedo marmorata. The primary structure of the peptide was established as Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2. This amino acid sequence is identical to that of residues (3–18) of scyliorhinin II (cas 112748-19-3) previously isolated from the intestine of the common dogfish (Scyliorhinus canicula). The presence of the truncated peptide, lacking Ser-Pro, in the Torpedo gut suggests that scyliorhinin II may be a substrate for an enzyme with dipeptidylpeptidase IV-like specificity. The data support previous assertions that strong evolutionary pressure has acted within the elasmobranch subclass of chondrichthyean fish to conserve the structures of regulatory peptides.

We also recommend Trading Suppliers and Manufacturers of scyliorhinin II (cas 112748-19-3). Pls Click Website Link as below: cas 112748-19-3 suppliers

Prev:Isolation and purification of CLEMASTANIN B (cas 112747-98-5) and indigoticoside A from Radix Isatidis by high-speed counter-current chromatography
Next:Synthesis of novel 2,4-bis(substituted phenoxy)-6-(phenylthio) pyrimidine analogs and their antimicrobial activities)